E2F3-A novel repressor of the ARF/p53 pathway

Doron Ginsberg

doi:10.1016/j.devcel.2004.05.012

E2F3-A novel repressor of the ARF/p53 pathway

Doron Ginsberg

Weizmann Institute of Science

Research output: Contribution to journal › Review article › peer-review

23 Scopus citations

Abstract

The Arf tumor suppressor is a key component of the p53 tumor surveillance pathway, and its expression is activated by abnormal proliferation signals. In a recent paper, Lees and coworkers investigate the regulation of Arf expression by E2Fs and demonstrate that in normal cells E2F3 is a pivotal repressor of Arf.

Original language	English
Pages (from-to)	742-743
Number of pages	2
Journal	Developmental Cell
Volume	6
Issue number	6
DOIs	https://doi.org/10.1016/j.devcel.2004.05.012
State	Published - Jun 2004
Externally published	Yes

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10.1016/j.devcel.2004.05.012

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abstract = "The Arf tumor suppressor is a key component of the p53 tumor surveillance pathway, and its expression is activated by abnormal proliferation signals. In a recent paper, Lees and coworkers investigate the regulation of Arf expression by E2Fs and demonstrate that in normal cells E2F3 is a pivotal repressor of Arf.",

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E2F3-A novel repressor of the ARF/p53 pathway

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