e23D, a database of A-to-I RNA editing sites from human, mouse and fly mapped to evolutionary related protein 3D structures, is presented. Genomic coordinates of A-to-I RNA editing sites are converted to protein coordinates and mapped onto 3D structures from PDB or theoretical models from ModBase. e23D allows visualization of the protein structure, modeling of recoding events and orientation of the editing with respect to nearby genomic functional sites from databases of disease causing mutations and genomic polymorphism. Availability and Implementation: http://www.sheba-cancer.org.il/e23D Contact: or Eran.Eyal@sheba.health.gov.il.
|Number of pages||3|
|Early online date||19 Apr 2016|
|State||Published - 15 Jul 2016|
Bibliographical noteFunding Information:
The work was supported by grants from the Varda and Boaz Dotan Research Center in Hemato-oncology affiliated with the CBRC of Tel Aviv University, Flight Attendant Medical Research Institute (FAMRI), Israeli Centers of Excellence (I-CORE) Program (ISF grants no. 41/11 and no. 1796/12).
© 2016 The Author 2016. Published by Oxford University Press. All rights reserved.