Dynamics of polymer chain collapse into compact states

The folding of polymer chains into packed cubic states was studied using molecular dynamics simulation methods. The polymer based on a chain linked sites moving in the continuum, includes both excluded volume and torsional interactions. The different native-state packing arrangements and chain lengths were also explored. It was found that the organization of the native state affect the ability of the chain to fold successfully and the nature of the folding pathways as the system was gradually cooled.