Abstract
Single-molecule detection and spectroscopy by laser induced fluorescence offer many applications to life sciences. We review recent techniques and experiments based on the detection and spectroscopy of two near-by molecules. The spectroscopic signature of the light emitted from the two molecules can be used to measure the distance, orientation and relative dynamics between biological macromolecules.
| Original language | English |
|---|---|
| Pages (from-to) | 1115-1128 |
| Number of pages | 14 |
| Journal | IEEE Journal of Selected Topics in Quantum Electronics |
| Volume | 2 |
| Issue number | 4 |
| DOIs | |
| State | Published - Dec 1996 |
| Externally published | Yes |
Bibliographical note
Funding Information:Manuscript received October 3, 1996; revised December 19, 1996. This work was supported by the Laboratory Directed Research and Development Program of Lawrence Berkeley National Laboratory under U.S. Department of Energy Contract DE-AC03-76SF00098 and by the Office of Naval Research under Contract N00014-95-F-0099.
Funding
Manuscript received October 3, 1996; revised December 19, 1996. This work was supported by the Laboratory Directed Research and Development Program of Lawrence Berkeley National Laboratory under U.S. Department of Energy Contract DE-AC03-76SF00098 and by the Office of Naval Research under Contract N00014-95-F-0099.
| Funders | Funder number |
|---|---|
| Office of Naval Research | N00014-95-F-0099 |
| U.S. Department of Energy | DE-AC03-76SF00098 |
| Lawrence Berkeley National Laboratory |