Dual-molecule spectroscopy: Molecular rulers for the study of biological macromolecules

T. Ha, Th Enderle, D. S. Chemla, S. Weiss

Research output: Contribution to journalArticlepeer-review

43 Scopus citations


Single-molecule detection and spectroscopy by laser induced fluorescence offer many applications to life sciences. We review recent techniques and experiments based on the detection and spectroscopy of two near-by molecules. The spectroscopic signature of the light emitted from the two molecules can be used to measure the distance, orientation and relative dynamics between biological macromolecules.

Original languageEnglish
Pages (from-to)1115-1128
Number of pages14
JournalIEEE Journal of Selected Topics in Quantum Electronics
Issue number4
StatePublished - Dec 1996
Externally publishedYes

Bibliographical note

Funding Information:
Manuscript received October 3, 1996; revised December 19, 1996. This work was supported by the Laboratory Directed Research and Development Program of Lawrence Berkeley National Laboratory under U.S. Department of Energy Contract DE-AC03-76SF00098 and by the Office of Naval Research under Contract N00014-95-F-0099.


Dive into the research topics of 'Dual-molecule spectroscopy: Molecular rulers for the study of biological macromolecules'. Together they form a unique fingerprint.

Cite this