Abstract
For the past five years we have used a double-balloon device for extraovular installation of prostaglandin solution for termination of midtrimester pregnancy. In 340 consecutive cases a success rate of 91% (abortions within 24 hours) was achieved, with a mean instillation-to- abortion interval of 17.5 ± 6.5 (SD) hours in nulliparas versus 12.8 ± 6.1 in multiparas (P < .005). The instillation of continuous, low-dose prostaglandin solution into the extraovular space resulted in very few side effects and no complications. Furthermore, the technique was used successfully in women who had undergone one or more cesarean sections in the past. The use of prostaglandin E 2 (PGE 2) resulted in shorter installation- to-abortion intervals than did prostaglandin F(2α) (P < .01); 500 μg/h of PGE 2 solution was needed in nulliparas, whereas 250 sufficed in multiparas.
| Original language | English |
|---|---|
| Pages (from-to) | 56-62 |
| Number of pages | 7 |
| Journal | Journal of Reproductive Medicine |
| Volume | 40 |
| Issue number | 1 |
| State | Published - Jan 1995 |
| Externally published | Yes |