Dopamine D4 receptor gene polymorphism and personality traits in healthy volunteers

M. L. Persson; D. Wassermann; T. Geijer; A. Frisch; R. Rockah; E. Michaelovsky; A. Apter; A. Weizmann; E. G. Jönsson; H. Bergmann

doi:10.1007/s004060070025

Dopamine D4 receptor gene polymorphism and personality traits in healthy volunteers

M. L. Persson, D. Wassermann, T. Geijer, A. Frisch, R. Rockah, E. Michaelovsky, A. Apter, A. Weizmann, E. G. Jönsson, H. Bergmann

Research output: Contribution to journal › Article › peer-review

27 Scopus citations

Abstract

An association between long alleles of a variable number tandem repeat (VNTR) polymorphism in the dopamine receptor D4 gene and the extraversion related personality traits Excitement and Novelty Seeking has been reported in healthy subjects. In an attempt to replicate the previous findings, 256 healthy Caucasian volunteers were analysed for a potential relationship between the dopamine receptor D4 exon III VNTR polymorphism and Extraversion as assessed by the Revised Neo Personality Inventory (NEO PI-R). The present study did not yield evidence for an association between Extraversion and the dopamine receptor D4 polymorphism.

Original language	English
Pages (from-to)	203-206
Number of pages	4
Journal	European Archives of Psychiatry and Clinical Neuroscience
Volume	250
Issue number	4
DOIs	https://doi.org/10.1007/s004060070025
State	Published - 2000
Externally published	Yes

Bibliographical note

Funding Information:
Acknowledgements This investigation was supported by the Fred-rik and Ingrid Thuring Foundation, the Bror Gadelius Memory Fund, the Golden Gate Foundation, the Söderström-Königska Foundation, the Scandia insurance company and the Sarah and Moshe Mayer Foundation. We thank Lotta Lindström and Lars Holmberg, Centre for Suicide Research and Prevention, Kjerstin Lind and Alexandra Tylec, Psychiatry Section, Karolinska Institutet and Gunnar Hilm, Clinical Alcohol and Drug Addiction Research Section, Karolinska Hospital, for excellent technical assistance.

Funding

Acknowledgements This investigation was supported by the Fred-rik and Ingrid Thuring Foundation, the Bror Gadelius Memory Fund, the Golden Gate Foundation, the Söderström-Königska Foundation, the Scandia insurance company and the Sarah and Moshe Mayer Foundation. We thank Lotta Lindström and Lars Holmberg, Centre for Suicide Research and Prevention, Kjerstin Lind and Alexandra Tylec, Psychiatry Section, Karolinska Institutet and Gunnar Hilm, Clinical Alcohol and Drug Addiction Research Section, Karolinska Hospital, for excellent technical assistance.

Funders	Funder number
Bror Gadelius Memory Fund
Fred-rik and Ingrid Thuring Foundation
Golden Gate Foundation
Söderström-Königska Foundation

Keywords

Dopamine receptor D4
Excitement-Seeking
Genetics
Personality inventory
Polymorphism

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1007/s004060070025

Cite this

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abstract = "An association between long alleles of a variable number tandem repeat (VNTR) polymorphism in the dopamine receptor D4 gene and the extraversion related personality traits Excitement and Novelty Seeking has been reported in healthy subjects. In an attempt to replicate the previous findings, 256 healthy Caucasian volunteers were analysed for a potential relationship between the dopamine receptor D4 exon III VNTR polymorphism and Extraversion as assessed by the Revised Neo Personality Inventory (NEO PI-R). The present study did not yield evidence for an association between Extraversion and the dopamine receptor D4 polymorphism.",

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AU - Michaelovsky, E.

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Dopamine D4 receptor gene polymorphism and personality traits in healthy volunteers

Abstract

Bibliographical note

Funding

Keywords

UN SDGs

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