DNA Computation in Medicine

Noam Mamet, Ido Bachelet

Research output: Chapter in Book/Report/Conference proceedingChapterpeer-review

Abstract

DNA is the hereditary component; this molecule encodes the genetic information for living organisms. In this chapter, the DNA molecule in the different works is being used as a raw material, building block, and molecular tool, using its unique traits and the research tools developed in years of study done around this molecule. One common technique to analyze the lengths of strands in a DNA sample is gel electrophoresis. In this method, the sample is loaded into a well found in the gel and then, subjected to an electric field, the DNA strands are pulled through the gel matrix. The tractability of Watson-Crick pairing provides control over the molecule at the nanoscale. Its predictable features enable people to program its behavior and to design reproducible complex cascades of events. The toehold-mediated strand displacement is a process in which a strand can take the place of another strand already found in a double-stranded formation.

Original languageEnglish
Title of host publicationWireless Computing in Medicine
Subtitle of host publicationFrom Nano to Cloud with Ethical and Legal Implications
Publisherwiley
Pages359-375
Number of pages17
ISBN (Electronic)9781118993620
ISBN (Print)9781118993590
DOIs
StatePublished - 1 Jul 2016

Bibliographical note

Publisher Copyright:
© 2016 John Wiley & Sons, Inc. All rights reserved.

Keywords

  • DNA computation
  • DNA molecule
  • DNA origami
  • Gel electrophoresis
  • Hereditary component
  • Toehold-mediated strand displacement

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