DNA computation: Applications and perspectives

Somnath Tagore, Saurav Bhattacharya, Md Ataul Islam, Md Lutful Islam

Research output: Contribution to journalArticlepeer-review

11 Scopus citations

Abstract

The computational capability of living systems has intrigued researchers for years. Primarily, the focus has been on implementing aspects of living systems in computational devices. Computer literal peoples expand their hand to the molecular biologist and chemist to explore the potential for computation of biological molecules line Deoxyribonucleic Acid (DNA) and Ribonucleic Acid (RNA) which are information carrying molecules. In this context, DNA computation is basically a collection of specially selected DNA strands whose combinations will result in the solution to some problems. DNA computation rather DNA-based computing is at the intersection of several threads of research. Main advantages of DNA computation are miniaturization and parallelism over conventional silicon-based machines. The informationbearing capability of DNA molecules is a cornerstone of modern theories of genetics and molecular biology. In this paper we have tried to focus on some key issues regarding the used and implementation DNA-based devices in life science field. We have also tried to suggest its advantage over silicon computers.

Original languageEnglish
Pages (from-to)234-243
Number of pages10
JournalJournal of Proteomics and Bioinformatics
Volume3
Issue number7
DOIs
StatePublished - 2010
Externally publishedYes

Keywords

  • Annealing
  • Complexity
  • Graphs
  • Hamiltonian path
  • Ligation

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