Direction of magnetoencephalography sources associated with feedback and feedforward contributions in a visual object recognition task

Seppo P. Ahlfors, Stephanie R. Jones, Jyrki Ahveninen, Matti S. Hämäläinen, John W. Belliveau, Moshe Bar

Research output: Contribution to journalArticlepeer-review

18 Scopus citations

Abstract

Identifying inter-area communication in terms of the hierarchical organization of functional brain areas is of considerable interest in human neuroimaging. Previous studies have suggested that the direction of magneto- and electroencephalography (MEG, EEG) source currents depend on the layer-specific input patterns into a cortical area. We examined the direction in MEG source currents in a visual object recognition experiment in which there were specific expectations of activation in the fusiform region being driven by either feedforward or feedback inputs. The source for the early non-specific visual evoked response, presumably corresponding to feedforward driven activity, pointed outward, i.e., away from the white matter. In contrast, the source for the later, object-recognition related signals, expected to be driven by feedback inputs, pointed inward, toward the white matter. Associating specific features of the MEG/EEG source waveforms to feedforward and feedback inputs could provide unique information about the activation patterns within hierarchically organized cortical areas.

Original languageEnglish
Pages (from-to)149-154
Number of pages6
JournalNeuroscience Letters
Volume585
DOIs
StatePublished - 12 Jan 2015

Bibliographical note

Publisher Copyright:
© 2014 Elsevier Ireland Ltd.

Keywords

  • Bottom-up
  • Cerebral cortex
  • Current dipole
  • Magnetoencephalography
  • Top-down

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