Direct Measurement of the Isomerization Barrier of the Isolated Retinal Chromophore

J. Dilger; L. Musbat; M. Sheves; A. B. Bochenkova; D. E. Clemmer; Y. Toker

doi:10.1063/1.4922826

Direct Measurement of the Isomerization Barrier of the Isolated Retinal Chromophore

J. Dilger, L. Musbat, M. Sheves, A. B. Bochenkova, D. E. Clemmer, Y. Toker

Department of Physics

Research output: Contribution to journal › Article › peer-review

Abstract

Isomerizations of the retinal chromophore were investigated using the IMS-IMS technique. Four different structural features of the chromophore were observed, isolated, excited collisionally, and the resulting isomer and fragment distributions were measured. By establishing the threshold activation voltages for isomerization for each of the reaction pathways, and by measuring the threshold activation voltage for fragmentation, the relative energies of the isomers as well as the energy barriers for isomerization were determined. The energy barrier for a single cis–trans isomerization is (0.64±0.05) eV, which is significantly lower than that observed for the reaction within opsin proteins.

Original language	English
Pages (from-to)	4830-4934
Number of pages	5
Journal	Angewandte Chemie
Volume	127
Issue number	16
DOIs	https://doi.org/10.1063/1.4922826
State	Published - 2015

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10.1063/1.4922826

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title = "Direct Measurement of the Isomerization Barrier of the Isolated Retinal Chromophore",

abstract = "Isomerizations of the retinal chromophore were investigated using the IMS-IMS technique. Four different structural features of the chromophore were observed, isolated, excited collisionally, and the resulting isomer and fragment distributions were measured. By establishing the threshold activation voltages for isomerization for each of the reaction pathways, and by measuring the threshold activation voltage for fragmentation, the relative energies of the isomers as well as the energy barriers for isomerization were determined. The energy barrier for a single cis–trans isomerization is (0.64±0.05) eV, which is significantly lower than that observed for the reaction within opsin proteins.",

author = "J. Dilger and L. Musbat and M. Sheves and Bochenkova, {A. B.} and Clemmer, {D. E.} and Y. Toker",

year = "2015",

doi = "10.1063/1.4922826",

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T1 - Direct Measurement of the Isomerization Barrier of the Isolated Retinal Chromophore

AU - Dilger, J.

AU - Musbat, L.

AU - Sheves, M.

AU - Bochenkova, A. B.

AU - Clemmer, D. E.

AU - Toker, Y.

PY - 2015

Y1 - 2015

N2 - Isomerizations of the retinal chromophore were investigated using the IMS-IMS technique. Four different structural features of the chromophore were observed, isolated, excited collisionally, and the resulting isomer and fragment distributions were measured. By establishing the threshold activation voltages for isomerization for each of the reaction pathways, and by measuring the threshold activation voltage for fragmentation, the relative energies of the isomers as well as the energy barriers for isomerization were determined. The energy barrier for a single cis–trans isomerization is (0.64±0.05) eV, which is significantly lower than that observed for the reaction within opsin proteins.

AB - Isomerizations of the retinal chromophore were investigated using the IMS-IMS technique. Four different structural features of the chromophore were observed, isolated, excited collisionally, and the resulting isomer and fragment distributions were measured. By establishing the threshold activation voltages for isomerization for each of the reaction pathways, and by measuring the threshold activation voltage for fragmentation, the relative energies of the isomers as well as the energy barriers for isomerization were determined. The energy barrier for a single cis–trans isomerization is (0.64±0.05) eV, which is significantly lower than that observed for the reaction within opsin proteins.

UR - http://onlinelibrary.wiley.com/doi/10.1002/ange.201411894/full

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VL - 127

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JO - Angewandte Chemie

JF - Angewandte Chemie

IS - 16

ER -

Direct Measurement of the Isomerization Barrier of the Isolated Retinal Chromophore

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