Abstract
We report the first examples of nonsymmetrical dibenzodiazocinediones, mono-, di-, tri- and tetra-substituted in the aromatic rings including a benzo pyridino diazocine, by a new short method without the requirement of protection. The procedure involves conversion of an anthranilic acid to its sulfinamide lactone followed by direct heating with a different N-alkylanthranilic acid.
| Original language | English |
|---|---|
| Pages (from-to) | 1377-1379 |
| Number of pages | 3 |
| Journal | Tetrahedron Letters |
| Volume | 45 |
| Issue number | 7 |
| DOIs | |
| State | Published - 9 Feb 2004 |
Bibliographical note
Funding Information:Support of this research by Compugen Ltd. and by the Marcus Center for Medicinal and Pharmaceutical Chemistry at Bar-Ilan University is gratefully acknowledged.
Funding
Support of this research by Compugen Ltd. and by the Marcus Center for Medicinal and Pharmaceutical Chemistry at Bar-Ilan University is gratefully acknowledged.
| Funders |
|---|
| Compugen Ltd. |
| Bernard W. Marcus Center for Medicinal Chemistry, Bar-Ilan University |
Keywords
- Anthranilic acids
- Diazocine
- Dibenzodiazocine
- Dilactam synthesis
- Eight-membered ring
Fingerprint
Dive into the research topics of 'Dilactams. Synthesis of nonsymmetrical dibenzodiazocinediones'. Together they form a unique fingerprint.Cite this
- APA
- Author
- BIBTEX
- Harvard
- Standard
- RIS
- Vancouver