Digital optical microscope (housing inside biosafety cabinet): A promising imaging technology for micro- and cell-biology, and histopathology

Anamika Elizabeth Kujur; S. R. Rinsa; Mayanglambam Suheshkumar Singh

doi:10.1117/12.2502117

Digital optical microscope (housing inside biosafety cabinet): A promising imaging technology for micro- and cell-biology, and histopathology

Anamika Elizabeth Kujur, S. R. Rinsa, Mayanglambam Suheshkumar Singh

Indian Institute of Science Education and Research Thiruvananthapuram

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › peer-review

Abstract

Conventional laboratory activities for research studies, more specifically in Biology and histopathology, involves back and forth movement of biological or tissue specimen all around the laboratory workspace - from Biosafety Cabinet (BSC) to workbench of microscopy imaging unit. This mobility imposes a serious concern of contamination of the biological specimen. We study design and develop of an optical microscopic imaging system - that can be adapted inside BSC - which remains as a challenge from technological aspects. This (automated) system with motion control in all 3-directions facilitates recording as well as observation of the biological procedure (in real time) being performed inside BSC. Experimental validation studies were carried out in a diverse biological specimen and demonstrate that this imaging technology facilitates study of miniscule biological specimen (cells and bacteria) not only easy but also enable to undertake sophisticated biological/clinical procedures.

Original language	English
Title of host publication	Medical Imaging 2019
Subtitle of host publication	Physics of Medical Imaging
Editors	Taly Gilat Schmidt, Guang-Hong Chen, Hilde Bosmans
Publisher	SPIE
ISBN (Electronic)	9781510625433
DOIs	https://doi.org/10.1117/12.2502117
State	Published - 2019
Externally published	Yes
Event	Medical Imaging 2019: Physics of Medical Imaging - San Diego, United States Duration: 17 Feb 2019 → 20 Feb 2019

Publication series

Name	Progress in Biomedical Optics and Imaging - Proceedings of SPIE
Volume	10948
ISSN (Print)	1605-7422

Conference

Conference	Medical Imaging 2019: Physics of Medical Imaging
Country/Territory	United States
City	San Diego
Period	17/02/19 → 20/02/19

Bibliographical note

Publisher Copyright:
© SPIE. Downloading of the abstract is permitted for personal use only.

Keywords

Biosafety cabinet (BSC)
Microscopic imaging
Optical microscope
Splitting of clustered cells

Access to Document

10.1117/12.2502117

Cite this

Elizabeth Kujur, A., Rinsa, S. R., & Singh, M. S. (2019). Digital optical microscope (housing inside biosafety cabinet): A promising imaging technology for micro- and cell-biology, and histopathology. In T. G. Schmidt, G.-H. Chen, & H. Bosmans (Eds.), Medical Imaging 2019: Physics of Medical Imaging Article 109483T (Progress in Biomedical Optics and Imaging - Proceedings of SPIE; Vol. 10948). SPIE. https://doi.org/10.1117/12.2502117

Elizabeth Kujur, Anamika ; Rinsa, S. R. ; Singh, Mayanglambam Suheshkumar. / Digital optical microscope (housing inside biosafety cabinet) : A promising imaging technology for micro- and cell-biology, and histopathology. Medical Imaging 2019: Physics of Medical Imaging. editor / Taly Gilat Schmidt ; Guang-Hong Chen ; Hilde Bosmans. SPIE, 2019. (Progress in Biomedical Optics and Imaging - Proceedings of SPIE).

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Elizabeth Kujur, A, Rinsa, SR & Singh, MS 2019, Digital optical microscope (housing inside biosafety cabinet): A promising imaging technology for micro- and cell-biology, and histopathology. in TG Schmidt, G-H Chen & H Bosmans (eds), Medical Imaging 2019: Physics of Medical Imaging., 109483T, Progress in Biomedical Optics and Imaging - Proceedings of SPIE, vol. 10948, SPIE, Medical Imaging 2019: Physics of Medical Imaging, San Diego, United States, 17/02/19. https://doi.org/10.1117/12.2502117

Digital optical microscope (housing inside biosafety cabinet): A promising imaging technology for micro- and cell-biology, and histopathology. / Elizabeth Kujur, Anamika; Rinsa, S. R.; Singh, Mayanglambam Suheshkumar.
Medical Imaging 2019: Physics of Medical Imaging. ed. / Taly Gilat Schmidt; Guang-Hong Chen; Hilde Bosmans. SPIE, 2019. 109483T (Progress in Biomedical Optics and Imaging - Proceedings of SPIE; Vol. 10948).

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › peer-review

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Elizabeth Kujur A, Rinsa SR, Singh MS. Digital optical microscope (housing inside biosafety cabinet): A promising imaging technology for micro- and cell-biology, and histopathology. In Schmidt TG, Chen GH, Bosmans H, editors, Medical Imaging 2019: Physics of Medical Imaging. SPIE. 2019. 109483T. (Progress in Biomedical Optics and Imaging - Proceedings of SPIE). doi: 10.1117/12.2502117

Digital optical microscope (housing inside biosafety cabinet): A promising imaging technology for micro- and cell-biology, and histopathology

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Keywords

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