Digger: directed annotation of immunoglobulin and T cell receptor V, D, and J gene sequences and assemblies

William D. Lees, Swati Saha, Gur Yaari, Corey T. Watson

Research output: Contribution to journalArticlepeer-review

Abstract

Knowledge of immunoglobulin and T cell receptor encoding genes is derived from high-quality genomic sequencing. High-throughput sequencing is delivering large volumes of data, and precise, high-throughput approaches to annotation are needed. Digger is an automated tool that identifies coding and regulatory regions of these genes, with results comparable to those obtained by current expert curational methods. Availability and implementation: Digger is published under open source license at https://github.com/williamdlees/Digger and is available as a Python package and a Docker container.

Original languageEnglish
Article numberbtae144
JournalBioinformatics
Volume40
Issue number3
DOIs
StatePublished - 4 Mar 2024

Bibliographical note

Publisher Copyright:
© The Author(s) 2024. Published by Oxford University Press. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited.

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