TY - JOUR
T1 - Diffusion rate determines balance between extinction and proliferation in birth-death processes
AU - Behar, Hilla
AU - Agranovich, Alexandra
AU - Louzoun, Yoram
PY - 2013/6
Y1 - 2013/6
N2 - We here study spatially extended catalyst induced growth processes. This type of process exists in multiple domains of biology, ranging from ecology (nutrients and growth), through immunology (antigens and lymphocytes) to molecular biology (signaling molecules initiating signaling cascades). Such systems often exhibit an extinction-proliferation transition, where varying some parameters can lead to either extinction or survival of the reactants. When the stochasticity of the reactions, the presence of discrete reactants and their spatial distribution is incorporated into the analysis, a non-uniform reactant distribution emerges, even when all parameters are uniform in space. Using a combination of Monte Carlo simulation and percolation theory based estimations; the asymptotic behavior of such systems is studied. In all studied cases, it turns out that the overall survival of the reactant population in the long run is based on the size and shape of the reactant aggregates, their distribution in space and the reactant diffusion rate. We here show that for a large class of models, the reactant density is maximal at intermediate diffusion rates and low or zero at either very high or very low diffusion rates. We give multiple examples of such system and provide a generic explanation for this behavior. The set of models presented here provides a new insight on the population dynamics in chemical, biological and ecological systems.
AB - We here study spatially extended catalyst induced growth processes. This type of process exists in multiple domains of biology, ranging from ecology (nutrients and growth), through immunology (antigens and lymphocytes) to molecular biology (signaling molecules initiating signaling cascades). Such systems often exhibit an extinction-proliferation transition, where varying some parameters can lead to either extinction or survival of the reactants. When the stochasticity of the reactions, the presence of discrete reactants and their spatial distribution is incorporated into the analysis, a non-uniform reactant distribution emerges, even when all parameters are uniform in space. Using a combination of Monte Carlo simulation and percolation theory based estimations; the asymptotic behavior of such systems is studied. In all studied cases, it turns out that the overall survival of the reactant population in the long run is based on the size and shape of the reactant aggregates, their distribution in space and the reactant diffusion rate. We here show that for a large class of models, the reactant density is maximal at intermediate diffusion rates and low or zero at either very high or very low diffusion rates. We give multiple examples of such system and provide a generic explanation for this behavior. The set of models presented here provides a new insight on the population dynamics in chemical, biological and ecological systems.
KW - AB model
KW - Adaption
KW - Directed percolation
KW - Localization
KW - Logistic growth
UR - http://www.scopus.com/inward/record.url?scp=84877049980&partnerID=8YFLogxK
U2 - 10.3934/mbe.2013.10.523
DO - 10.3934/mbe.2013.10.523
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C2 - 23906134
AN - SCOPUS:84877049980
SN - 1547-1063
VL - 10
SP - 523
EP - 550
JO - Mathematical Biosciences and Engineering
JF - Mathematical Biosciences and Engineering
IS - 3
ER -