Diagnostic applications of nuclear medicine: Lung and mediastinal tumors

Elite Arnon, Thida Win, Ora Israel, Ludmila Guralnik, Simona Ben-Haim

Research output: Chapter in Book/Report/Conference proceedingChapterpeer-review

Abstract

While CT and MRI provide high-resolution anatomic assessment of lung and mediastinal malignancies, [18F]FDG imaging is superior in differentiating benign from malignant lymphadenopathy and in the detection of distant metastases. Pre-therapy assessment with [18F]FDG can provide important prognostic information. In addition [18F]FDG PET/CT can eliminate about half of futile thoracotomies and is therefore recommended for staging of lung and mediastinal tumors. [18F]FDG imaging is also indicated in the diagnosis of recurrent disease and in monitoring treatment. [18F] FDG PET/CT has been introduced for radiation planning, enabling refining treatment volumes to allow increased dose in target volume and reduced toxicity to nontarget tissues. Although [18F]FDG is the most widely used tracer in oncology, other PET tracers are evaluated with specific clinical and research goals and may have a future role in the management of lung malignancies.

Original languageEnglish
Title of host publicationNuclear Oncology
Subtitle of host publicationFrom Pathophysiology to Clinical Applications
PublisherSpringer International Publishing
Pages639-684
Number of pages46
ISBN (Electronic)9783319262369
ISBN (Print)9783319262345
DOIs
StatePublished - 27 Oct 2017
Externally publishedYes

Bibliographical note

Publisher Copyright:
© Springer International Publishing Switzerland 2017. All rights reserved.

Keywords

  • Lung and mediastinal tumor imaging
  • Lung cancer
  • Staging of lung and mediastinal tumors
  • [F]FDG imaging in lung cancer

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