Abstract
While CT and MRI provide high-resolution anatomic assessment of lung and mediastinal malignancies, [18F]FDG imaging is superior in differentiating benign from malignant lymphadenopathy and in the detection of distant metastases. Pre-therapy assessment with [18F]FDG can provide important prognostic information. In addition [18F]FDG PET/CT can eliminate about half of futile thoracotomies and is therefore recommended for staging of lung and mediastinal tumors. [18F]FDG imaging is also indicated in the diagnosis of recurrent disease and in monitoring treatment. [18F] FDG PET/CT has been introduced for radiation planning, enabling refining treatment volumes to allow increased dose in target volume and reduced toxicity to nontarget tissues. Although [18F]FDG is the most widely used tracer in oncology, other PET tracers are evaluated with specific clinical and research goals and may have a future role in the management of lung malignancies.
Original language | English |
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Title of host publication | Nuclear Oncology |
Subtitle of host publication | From Pathophysiology to Clinical Applications |
Publisher | Springer International Publishing |
Pages | 639-684 |
Number of pages | 46 |
ISBN (Electronic) | 9783319262369 |
ISBN (Print) | 9783319262345 |
DOIs | |
State | Published - 27 Oct 2017 |
Externally published | Yes |
Bibliographical note
Publisher Copyright:© Springer International Publishing Switzerland 2017. All rights reserved.
Keywords
- Lung and mediastinal tumor imaging
- Lung cancer
- Staging of lung and mediastinal tumors
- [F]FDG imaging in lung cancer