Diagnosis and treatment of primary non-Hodgkin's lymphoma of the parotid gland: A retrospective study - Experience at the Northern Israel Oncology Center (1977-1999): A retrospective study - Experience at the Northern Israel Oncology Center (1977-1999)

Moshe E. Stein, A. Kuten, M. Ben-Shachar, K. Drumea, J. Zidan, E. Gez, N. Haim, R. Epelbaum

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2 Scopus citations

Abstract

Purpose: The treatment and outcome of primary parotid gland non-Hodgkin's lymphoma (PGL) has rarely been described. This retrospective study documents the clinicopathologic features and treatment results in this relatively rare entity. Patients and methods: This study was conducted on 11 patients diagnosed and treated for primary PGL over a period of 22 years. Results: Of the 4 male and 7 female patients, only one presented with the classic pattern of Sjögren's syndrome (SS) simultaneous with PGL, and only 4 patients demonstrated a low-grade Maltoma type. None of the patients had evidence of disease at the end of the primary treatment; 4 patients are alive and well from 6 months to 10 years after the end of treatment. Four patients relapsed and died due to therapy-resistant disease and 3 patients died of nonmalignant causes while in complete remission. Conclusion: The majority of patients with primary non-Hodgkin's lymphoma of the parotid gland present with early-stage disease. Accurate staging is mandatory. Low-grade, localized PGL can be treated successfully with primary radiotherapy alone. The aggressive type of PGL should be treated with combined chemoradiotherapy-based regimens.
Original languageEnglish
Pages (from-to)229-233
Number of pages5
JournalJournal of B.U.ON.
Volume7
Issue number3
StatePublished - 1 Jul 2002

Keywords

  • Chemoradiotherapy
  • Non-Hodgkin's lymphoma
  • Parotid gland
  • Salivary glands

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