Abstract
Purpose: The treatment and outcome of primary parotid gland non-Hodgkin's lymphoma (PGL) has rarely been described. This retrospective study documents the clinicopathologic features and treatment results in this relatively rare entity. Patients and methods: This study was conducted on 11 patients diagnosed and treated for primary PGL over a period of 22 years. Results: Of the 4 male and 7 female patients, only one presented with the classic pattern of Sjögren's syndrome (SS) simultaneous with PGL, and only 4 patients demonstrated a low-grade Maltoma type. None of the patients had evidence of disease at the end of the primary treatment; 4 patients are alive and well from 6 months to 10 years after the end of treatment. Four patients relapsed and died due to therapy-resistant disease and 3 patients died of nonmalignant causes while in complete remission. Conclusion: The majority of patients with primary non-Hodgkin's lymphoma of the parotid gland present with early-stage disease. Accurate staging is mandatory. Low-grade, localized PGL can be treated successfully with primary radiotherapy alone. The aggressive type of PGL should be treated with combined chemoradiotherapy-based regimens.
Original language | English |
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Pages (from-to) | 229-233 |
Number of pages | 5 |
Journal | Journal of B.U.ON. |
Volume | 7 |
Issue number | 3 |
State | Published - 1 Jul 2002 |
Keywords
- Chemoradiotherapy
- Non-Hodgkin's lymphoma
- Parotid gland
- Salivary glands