Diadenosine 5',5'-(Boranated)polyphosphonate analogues as selective nucleotide pyrophosphatase/phosphodiesterase inhibitors ^⊥

Keyphrases

• Nucleotide Pyrophosphatase/phosphodiesterase 100%
• Diadenosine 100%
• Phosphodiesterase Inhibitors 100%
• Polyps 100%
• Hydrolysis 50%
• NPP1 33%
• Ectonucleotidases 33%
• Phosphonates 16%
• Catabolism 16%
• New Analogs 16%
• Cell Surface 16%
• Dinucleotide 16%
• Agonistic Behavior 16%
• IC50 16%
• NTPDase 16%
• P2Y1 16%
• ATP Analogues 16%
• Health Disorders 16%
• Osteoarthritis 16%
• NTPDase1 16%
• Osteocarcinoma 16%
• NPP3 16%
• Purinergic Signaling 16%
• Borophosphate 16%
• P2Y2 Receptor 16%
• Extracellular nucleotides 16%
• Colon Cancer Cells 16%
• OH Groups 16%
• Phosphodiesterase Activity 16%
• Ap5A 16%

Biochemistry, Genetics and Molecular Biology

• Pyrophosphatase 100%
• Inorganic Pyrophosphatase 100%
• Phosphodiesterase 100%
• Enzymatic Hydrolysis 66%
• Adenosine Triphosphate 33%
• Nucleotidase 33%
• Surface Property 16%
• Colon 16%
• Cancer Cell 16%
• IC50 16%
• Eicosanoid Receptor 16%
• Adenosine Monophosphate 16%

Pharmacology, Toxicology and Pharmaceutical Science

• Nucleotide Pyrophosphatase 100%
• Phosphodiesterase Inhibitor 100%
• Phosphodiesterase 50%
• 5' Nucleotidase 33%
• Adenosine Triphosphate 33%
• Phosphonate 16%
• Osteoarthritis 16%
• Malignant Neoplasm 16%
• Adenosine Phosphate 16%
• Colon Cancer 16%
• Purinergic P2Y2 Receptor 16%
• Dinucleotide 16%
• Disease 16%
• IC50 16%