Development of biotechnology for commiphora wightii: a potent source of natural hypolipidemic and hypocholesterolemic drug

Sandeep Kumar; S. S. Suri; K. C. Sonie; K. G. Ramawat

doi:10.1007/1-4020-3213-7_8

Development of biotechnology for commiphora wightii: a potent source of natural hypolipidemic and hypocholesterolemic drug

Sandeep Kumar
, S. S. Suri
, K. C. Sonie
, K. G. Ramawat

Mohan Lal Sukhadia University

Research output: Chapter in Book/Report/Conference proceeding › Chapter › peer-review

2 Scopus citations

Abstract

Commiphora wightii has become an endangered species due to its overexploitation for its gum-resin. Guggulsterones present in gum-resin are potent lipid and cholesterol lowering natural agents. Drugs based on these are currently used clinically in India and Europe. The plant is endemic to Indian subcontinent, therefore major contributions on its biology, chemistry, pharmacology and biotechnology have been made by Indian scientists. Biotechnological approaches made for guggulsterone production by cell cultures and for its micropropagation are reviewed.

Original language	English
Title of host publication	Plant Biotechnology and Molecular Markers
Publisher	Springer Netherlands
Pages	129-143
Number of pages	15
ISBN (Print)	1402032137, 9781402019111
DOIs	https://doi.org/10.1007/1-4020-3213-7_8
State	Published - 2005
Externally published	Yes

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abstract = "Commiphora wightii has become an endangered species due to its overexploitation for its gum-resin. Guggulsterones present in gum-resin are potent lipid and cholesterol lowering natural agents. Drugs based on these are currently used clinically in India and Europe. The plant is endemic to Indian subcontinent, therefore major contributions on its biology, chemistry, pharmacology and biotechnology have been made by Indian scientists. Biotechnological approaches made for guggulsterone production by cell cultures and for its micropropagation are reviewed.",

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AU - Sonie, K. C.

AU - Ramawat, K. G.

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AB - Commiphora wightii has become an endangered species due to its overexploitation for its gum-resin. Guggulsterones present in gum-resin are potent lipid and cholesterol lowering natural agents. Drugs based on these are currently used clinically in India and Europe. The plant is endemic to Indian subcontinent, therefore major contributions on its biology, chemistry, pharmacology and biotechnology have been made by Indian scientists. Biotechnological approaches made for guggulsterone production by cell cultures and for its micropropagation are reviewed.

UR - https://www.scopus.com/pages/publications/33746041953

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PB - Springer Netherlands

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Development of biotechnology for commiphora wightii: a potent source of natural hypolipidemic and hypocholesterolemic drug

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