TY - CHAP
T1 - Development of biotechnology for commiphora wightii
T2 - a potent source of natural hypolipidemic and hypocholesterolemic drug
AU - Kumar, Sandeep
AU - Suri, S. S.
AU - Sonie, K. C.
AU - Ramawat, K. G.
PY - 2005
Y1 - 2005
N2 - Commiphora wightii has become an endangered species due to its overexploitation for its gum-resin. Guggulsterones present in gum-resin are potent lipid and cholesterol lowering natural agents. Drugs based on these are currently used clinically in India and Europe. The plant is endemic to Indian subcontinent, therefore major contributions on its biology, chemistry, pharmacology and biotechnology have been made by Indian scientists. Biotechnological approaches made for guggulsterone production by cell cultures and for its micropropagation are reviewed.
AB - Commiphora wightii has become an endangered species due to its overexploitation for its gum-resin. Guggulsterones present in gum-resin are potent lipid and cholesterol lowering natural agents. Drugs based on these are currently used clinically in India and Europe. The plant is endemic to Indian subcontinent, therefore major contributions on its biology, chemistry, pharmacology and biotechnology have been made by Indian scientists. Biotechnological approaches made for guggulsterone production by cell cultures and for its micropropagation are reviewed.
UR - http://www.scopus.com/inward/record.url?scp=33746041953&partnerID=8YFLogxK
U2 - 10.1007/1-4020-3213-7_8
DO - 10.1007/1-4020-3213-7_8
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AN - SCOPUS:33746041953
SN - 1402032137
SN - 9781402019111
SP - 129
EP - 143
BT - Plant Biotechnology and Molecular Markers
PB - Springer Netherlands
ER -