Detection of Hepatitis D Virus: Performance in the Community

Sophia Eilat-Tsanani, Amal Zoubi, Rawi Hazzan

Research output: Contribution to journalArticlepeer-review


Background: Hepatitis D virus may cause a disease at various severities in the presence of hepatitis B virus, using hepatitis B surface antigen (HBsAg) on the external envelope in its replication process. Thus, people identified with HBsAg in blood tests should also be tested for hepatitis D virus. Objectives: To describe the situation of performance of blood tests for detection of hepatitis D virus in patients positive for hepatitis surface antigen during 9 years in a population with heterogeneous origins in the north region of Israel. Methods: We conducted a retrospective study using the database of Clalit Health Services. Results: We found 3367 people were positive for HBsAg during the study period; 613 (18%) were tested for hepatitis D. People who tested for hepatitis D were younger (47.3 ± 15 years vs. 50.5) and showed a higher rate of visiting the gastroenterology clinic (80.6% vs. 41%). The rate of positive blood tests for hepatitis D was too small for analysis, but it still demonstrated tendency for higher rates in the Ethiopian Jewish group. Conclusions: The recommendation for performance of blood test for hepatitis D virus was followed to a small extent. Considering the ethnic diversity of the population in Israel, activities to raise rates of performance should be considered.

Original languageEnglish
Pages (from-to)529-532
Number of pages4
JournalIsrael Medical Association Journal
Issue number8
StatePublished - 1 Aug 2022

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© 2022 Israel Medical Association. All rights reserved.


  • blood tests
  • community base
  • hepatitis B
  • hepatitis B surface antigen (HBsAg)
  • hepatitis D


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