Dendritic Learning as a Paradigm Shift in Brain Learning

Shira Sardi, Roni Vardi, Amir Goldental, Yael Tugendhaft, Herut Uzan, Ido Kanter

Research output: Contribution to journalReview articlepeer-review

4 Scopus citations


Experimental and theoretical results reveal a new underlying mechanism for fast brain learning process, dendritic learning, as opposed to the misdirected research in neuroscience over decades, which is based solely on slow synaptic plasticity. The presented paradigm indicates that learning occurs in closer proximity to the neuron, the computational unit, dendritic strengths are self-oscillating, and weak synapses, which comprise the majority of our brain and previously were assumed to be insignificant, play a key role in plasticity. The new learning sites of the brain call for a reevaluation of current treatments for disordered brain functionality and for a better understanding of proper chemical drugs and biological mechanisms to maintain, control and enhance learning.

Original languageEnglish
Pages (from-to)1230-1232
Number of pages3
JournalACS Chemical Neuroscience
Issue number6
Early online date4 May 2018
StatePublished - 20 Jun 2018

Bibliographical note

Publisher Copyright:
© 2018 American Chemical Society.


  • Learning
  • deep learning
  • degenerative diseases
  • dendrites
  • synaptic plasticity


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