Demonstration of remote optical measurement configuration that correlates to glucose concentration in blood

Yevgeny Beiderman, Raz Blumenberg, Nir Rabani, Mina Teicher, Javier Garcia, Vicente Mico, Zeev Zalevsky

Research output: Contribution to journalArticlepeer-review

32 Scopus citations

Abstract

An optical approach allowing the extraction and the separation of remote vibration sources has recently been proposed. The approach has also been applied for medical related applications as blood pressure and heart beats monitoring. In this paper we demonstrate its capability to monitor glucose concentration in blood stream. The technique is based on the tracking of temporal changes of reflected secondary speckle produced in human skin (wrist) when being illuminated by a laser beam. A temporal change in skin's vibration profile generated due to blood pulsation is analyzed for estimating the glucose concentration. Experimental tests that were carried out in order to verify the proposed approach showed good match with the change of the glucose level at the positive slope stage as it was obtained from conventional reference measurement.

Original languageEnglish
Pages (from-to)858-870
Number of pages13
JournalBiomedical Optics Express
Volume2
Issue number4
DOIs
StatePublished - 1 Apr 2011

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