Datasets2Tools, repository and search engine for bioinformatics datasets, tools and canned analyses

Denis Torre, Patrycja Krawczuk, Kathleen M. Jagodnik, Alexander Lachmann, Zichen Wang, Lily Wang, Maxim V. Kuleshov, Avi Ma'Ayan

Research output: Contribution to journalArticlepeer-review

11 Scopus citations

Abstract

Biomedical data repositories such as the Gene Expression Omnibus (GEO) enable the search and discovery of relevant biomedical digital data objects. Similarly, resources such as OMICtools, index bioinformatics tools that can extract knowledge from these digital data objects. However, systematic access to pre-generated 'canned' analyses applied by bioinformatics tools to biomedical digital data objects is currently not available. Datasets2Tools is a repository indexing 31,473 canned bioinformatics analyses applied to 6,431 datasets. The Datasets2Tools repository also contains the indexing of 4,901 published bioinformatics software tools, and all the analyzed datasets. Datasets2Tools enables users to rapidly find datasets, tools, and canned analyses through an intuitive web interface, a Google Chrome extension, and an API. Furthermore, Datasets2Tools provides a platform for contributing canned analyses, datasets, and tools, as well as evaluating these digital objects according to their compliance with the findable, accessible, interoperable, and reusable (FAIR) principles. By incorporating community engagement, Datasets2Tools promotes sharing of digital resources to stimulate the extraction of knowledge from biomedical research data. Datasets2Tools is freely available from: http://amp.pharm.mssm.edu/datasets2tools.

Original languageEnglish
Article number180023
JournalScientific data
Volume5
DOIs
StatePublished - 27 Feb 2018
Externally publishedYes

Bibliographical note

Publisher Copyright:
© The Author(s) 2018.

Funding

This work is partially supported by the National Institutes of Health (NIH) grants U54HL127624, U54CA189201, and OT3OD025467 to AM.

FundersFunder number
National Institutes of HealthOT3OD025467, U54CA189201, U54HL127624
National Heart, Lung, and Blood InstituteT32HL007824

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