Cytoskeletal proteins as drug development targets for various diseases

Nancy J. Woolf, Avner Priel, Jack A. Tuszynski

Research output: Chapter in Book/Report/Conference proceedingChapterpeer-review

Abstract

In this chapter, we stress the importance of the cytoskeleton for various functions ofall eukaryotic cells. We outline how the impairment of key proteins of the cytoskeletoncan be implicated in the development of various diseases. Consequently, these aberrantproteins should become targets for drug development. Particular attention is paid toneurological disorders and cancer. In the latter case, various drugs have been used incancer chemotherapy, and many more are currently in development stages. A fewexamples are given to illustrate these concepts.

Original languageEnglish
Title of host publicationHypotheses in Clinical Medicine
PublisherNova Science Publishers, Inc.
Pages227-244
Number of pages18
ISBN (Print)9781622572762
StatePublished - 2013
Externally publishedYes

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