Abstract
It is important to define the accuracy of fine-needle aspiration cytology (FNAC) in the diagnosis of Warthin tumor (WT). This systematic review and meta-analysis evaluated the accuracy of FNAC in the diagnosis of WT in the parotid gland and WT growth rate. For determination of FNAC accuracy, 17 studies, encompassing 1710 cases, were included. Pulled random model estimates of sensitivity, specificity, PPV, and NPV were 93.7% (95%CI: 92.1, 95.3), 97.9% (95%CI: 97, 98.9), 93.3% (95%CI: 91.5, 95.1), and 97.4% (95%CI: 96.4, 98.4), respectively. FNAC is highly reliable for the diagnosis of WT of the parotid. The high PPV value suggests that patients with a cytological diagnosis of WT of the parotid may be assigned to active surveillance.
| Original language | English |
|---|---|
| Pages (from-to) | 2277-2287 |
| Number of pages | 11 |
| Journal | Head and Neck |
| Volume | 44 |
| Issue number | 10 |
| DOIs | |
| State | Published - Oct 2022 |
Bibliographical note
Publisher Copyright:© 2022 The Authors. Head & Neck published by Wiley Periodicals LLC.
Funding
We wish to thank Mr. Basem Hijazi from the Azrieli Faculty of Medicine, Bar Ilan University, for the statistical analysis and Galilee-CBR for editorial assistance. The article was written as part of the requirements of the Azrieli Faculty of Medicine, Bar-Ilan University, Safed, Israel, for an MD degree of Roie Fisher.
| Funders | Funder number |
|---|---|
| Azrieli Faculty of Medicine, Bar Ilan University | |
| Azrieli Faculty of Medicine, Bar-Ilan University |
Keywords
- Warthin tumor
- diagnosis
- fine-needle aspiration
- parotid gland