Cytokinin interaction with free radical metabolism and senescence: Effects on endogenous lipoxygenase and purine oxidation

Y. Y. Leshem, J. Wurzburger, S. Grossman, A. A. Frimer

Research output: Contribution to journalArticlepeer-review

49 Scopus citations

Abstract

A typical system comprising xanthine‐xanthine oxidase, which produces superoxide free radicals, significantly increased endogenous levels of the senescence‐associated lipoxygenase enzyme while cytokinin reversed this effect. It is suggested that in its interaction with free radicals cytokinin may have a dual effect: a) it may inhibit purine oxidation by the formation of a 2,8 dihydroxy purine which lowers the substrate affinity of xanthine oxidase; b) it may act as a direct free radical scavenger by virtue of H abstraction from the α‐carbon atom in the amine bond.

Original languageEnglish
Pages (from-to)9-12
Number of pages4
JournalPhysiologia Plantarum
Volume53
Issue number1
DOIs
StatePublished - Sep 1981

Keywords

  • Free radicals
  • scavengers
  • xanthine
  • xanthine oxidase

Fingerprint

Dive into the research topics of 'Cytokinin interaction with free radical metabolism and senescence: Effects on endogenous lipoxygenase and purine oxidation'. Together they form a unique fingerprint.

Cite this