Cysteine sensing by plasmons of silver nanocubes

Eitan Elfassy, Yitzhak Mastai, Adi Salomon

Research output: Contribution to journalArticlepeer-review

14 Scopus citations


Noble metal nanoparticles are considered to be valuable nanostructures in the field of sensors due to their spectral response sensitivity to small changes in the surrounding refractive index which enables them to detect a small amount of molecules. In this research, we use silver nanocubes of about 50 nm length to detect low concentrations of cysteine, a semi-essential amino acid. Following cysteine adsorption onto the nanocubes, a redshift in the plasmonic modes was observed, enabling the detection of cysteine down to 10 μM and high sensitivity of about 125 nm/RIU (refractive index units). Furthermore, we found that multilayer adsorption of cysteine leads to the stabilization of the silver nanocubes. The cysteine growth onto the nanocubes was also characterized by high-resolution transmission electron microscopy (HR-TEM).

Original languageEnglish
Pages (from-to)110-114
Number of pages5
JournalJournal of Solid State Chemistry
StatePublished - 1 Sep 2016

Bibliographical note

Funding Information:
This research was supported by a Grant from the GIF, the German-Israeli Foundation for Scientific Research and Development (number 203785).

Publisher Copyright:
© 2016 Elsevier Inc. All rights reserved.


  • Chiral plasmonic systems
  • Cysteine
  • Localized surface plasmon resonance
  • Molecule-plasmon hybrid systems
  • Silver nanoparticles


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