TY - JOUR
T1 - Cumulative pregnancy rate following in-vitro fertilization
T2 - The significance of age and infertility aetiology
AU - Dor, J.
AU - Seidman, D. S.
AU - Ben-Shlomo, I.
AU - Levran, D.
AU - Ben-Rafael, Z.
AU - Mashiach, S.
PY - 1996/2
Y1 - 1996/2
N2 - During the years 1984-1992, 951 couples completed 2252 in-vitro fertilization (IVF) treatment cycles at the In-Vitro Fertilization Unit of The Chaim Sheba Medical Centre. This study was conducted to evaluate the success of IVF using the cumulative pregnancy rate (CPR), with special emphasis on the optimal number of treatment cycles, the age of the patients and female infertility factors. It was found that the CPR showed a constant rise during the six initial IVF treatments (56% CPR), and plateaued in the subsequent three cycles (63% CPR), Various female infertility factors did not influence this rate. Women ≥40 years of age have a significantly lower CPR, Thus, it was concluded that the CPR in IVF declined after the sixth initial treatment cycle, and in women ≥40 years of age. The infertility factor did not significantly influence CPR.
AB - During the years 1984-1992, 951 couples completed 2252 in-vitro fertilization (IVF) treatment cycles at the In-Vitro Fertilization Unit of The Chaim Sheba Medical Centre. This study was conducted to evaluate the success of IVF using the cumulative pregnancy rate (CPR), with special emphasis on the optimal number of treatment cycles, the age of the patients and female infertility factors. It was found that the CPR showed a constant rise during the six initial IVF treatments (56% CPR), and plateaued in the subsequent three cycles (63% CPR), Various female infertility factors did not influence this rate. Women ≥40 years of age have a significantly lower CPR, Thus, it was concluded that the CPR in IVF declined after the sixth initial treatment cycle, and in women ≥40 years of age. The infertility factor did not significantly influence CPR.
KW - Cumulative pregnancy rates
KW - Fertility by age
KW - IVF
KW - Infertility factor
UR - http://www.scopus.com/inward/record.url?scp=0029877478&partnerID=8YFLogxK
U2 - 10.1093/HUMREP/11.2.425
DO - 10.1093/HUMREP/11.2.425
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C2 - 8671236
AN - SCOPUS:0029877478
SN - 0268-1161
VL - 11
SP - 425
EP - 428
JO - Human Reproduction
JF - Human Reproduction
IS - 2
ER -