Cumulative conception rates following gonadotropin therapy

Jehoshua Dor, David J. Itzkowic, Shlomo Mashiach, Bruno Lunenfeld, David M. Serr

Research output: Contribution to journalArticlepeer-review

93 Scopus citations

Abstract

During the years 1963 to 1978, 515 patients were treated with HMG. They were divided into two groups depending upon the absence (Group I) or presence (Group II) of distinct endogenous estrogen activity. Group II patients were referred after failure of clomiphene therapy. None of the patients had mechanical or male infertility factors. The cumulative pregnancy rate (life table method) in Group I patients after six cycles of treatment was 91.2%. In 77 patients from Group I, further treatment was given for a second pregnancy after the first gonadotropin conception. In this group, the cumulative conception rate was 93.6% after eight cycles of treatment. In Group II the cumulative conception rate was 50% after 12 cycles of treatment. In both groups, the results were better in patients who were less than 35 years of age than those who were 35 or more when treated.

Original languageEnglish
Pages (from-to)102-105
Number of pages4
JournalAmerican Journal of Obstetrics and Gynecology
Volume136
Issue number1
DOIs
StatePublished - 1 Jan 1980
Externally publishedYes

Bibliographical note

Funding Information:
Supported zn part by Ford Foundation and thr Wwki Health Orga.niunkon.

Funding

Supported zn part by Ford Foundation and thr Wwki Health Orga.niunkon.

FundersFunder number
Ford Foundation

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