Cortical Spreading Depression of Leao: From Mitochondrial Function to Brain Metabolic Score (BMS)

Avraham Mayevsky, Judith Sonn

Research output: Book/ReportBookpeer-review

Abstract

This book focuses on energy metabolism and brain functions related to Cortical Spreading Depression of Leao (CSD), an important issue in brain pathophysiology. The first part of the book offers a comprehensive overview of the history and early research on CSD, and then discusses the recent advances in the technology used to map and monitor brain mitochondrial NADH redox state and other physiological functions during CSD. The chapters explore the connection between CSD and mitochondrial function under hypoxia, Ischemia and various drugs treatment, and provide a resource to scientists researching the development of CSD during various brain pathophysiological conditions. This book is essential to scientists and students working in the field of bioenergetics of the brain and various organs and tissues in the body. The use of this technology is also crucial and applicable in the neuroscience field.

Original languageEnglish
PublisherSpringer International Publishing
Number of pages420
ISBN (Electronic)9783031080685
ISBN (Print)9783031080678
DOIs
StatePublished - 1 Jan 2022

Bibliographical note

Publisher Copyright:
© The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer Nature Switzerland AG 2022.

Keywords

  • Anoxia and Hypoxia
  • Brain Energy Metabolism
  • Brain Ionic Homeostasis
  • Brain injuries
  • Brain pathophysiology
  • Cortical Spreading Depression
  • Effects of pharmacological Agents
  • Hyperbaric Hyperoxia
  • Leao’ Cortical Spreading Depression
  • Lifen Light Score
  • Microcirculation and cellular oxygenation
  • Mitochondrial Function in vivo
  • Patients monitoring
  • Traumatic Brain Injury

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