TY - JOUR
T1 - Core promoter functions in the regulation of gene expression of drosophila dorsal target genes
AU - Zehavi, Yonathan
AU - Kuznetsov, Olga
AU - Ovadia-Shochat, Avital
AU - Juven-Gershon, Tamar
PY - 2014/4/25
Y1 - 2014/4/25
N2 - Background: The Dorsal transcription factor regulates the dorsal-ventral developmental gene regulatory network by binding to enhancers. Results: The core promoters of multiple Dorsal target genes are evolutionarily conserved and functionally dependent on specific elements. Conclusion: The core promoter composition is an important determinant of the transcriptional outcome. Significance: Transcriptional regulation results from an interplay between enhancers and core promoter composition.
AB - Background: The Dorsal transcription factor regulates the dorsal-ventral developmental gene regulatory network by binding to enhancers. Results: The core promoters of multiple Dorsal target genes are evolutionarily conserved and functionally dependent on specific elements. Conclusion: The core promoter composition is an important determinant of the transcriptional outcome. Significance: Transcriptional regulation results from an interplay between enhancers and core promoter composition.
UR - http://www.scopus.com/inward/record.url?scp=84899426458&partnerID=8YFLogxK
U2 - 10.1074/jbc.M114.550251
DO - 10.1074/jbc.M114.550251
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C2 - 24634215
AN - SCOPUS:84899426458
SN - 0021-9258
VL - 289
SP - 11993
EP - 12004
JO - Journal of Biological Chemistry
JF - Journal of Biological Chemistry
IS - 17
ER -