Abstract
Large Language Models (LLMs) offer a scalable method to generate candidate concepts for ontology expansion. However, the outputs depend on LLMs’ sampling parameters such as “temperature.” A high temperature leads to increased hallucinations. We consider two hypotheses: (1) LLM outputs for higher temperatures should be supersets of corresponding outputs for lower temperatures; (2) Repeated LLM outputs for lower temperatures should converge to a steady state faster than for higher temperatures. A steady state is defined as k consecutive iterations with no new concepts generated (k-convergence). In this study, we analyzed Environmental Determinants of Health (EnDOH) concepts retrieved at sampling temperatures ranging from 0.1 to 1.0 using concept-structured prompting. Contrary to expectations, higher temperatures do not produce strict supersets of lower temperature outputs. To assess convergence towards a steady state we iteratively executed fixed prompts at different temperatures. Our results confirm that lower temperatures indeed lead to faster convergence.
| Original language | English |
|---|---|
| Title of host publication | Opening the Personal Gate between Technology and Health Care - Proceedings of MIE 2026 |
| Editors | Maria Hagglund, Lars Lindskold, Lenka Lhotska, Sara Marceglia, Enea Parimbelli, Lucia Sacchi, Paolo Soda, Lacramioara Stoicu-Tivadar, Pierangelo Veltri, Patrizia Vizza, Mauro Giacomini, Jaime Delgado, Theodoros N. Arvanitis, Elisavet Andrikopoulou, Arriel Benis, Gabriella Balestra, Riccardo Bellazzi, Parisis G. Gallos, Roberto Gatta, Daniele Roberto Giacobbe, Noemi Giordano |
| Publisher | IOS Press BV |
| Pages | 2279-2283 |
| Number of pages | 5 |
| ISBN (Electronic) | 9781643686615 |
| DOIs | |
| State | Published - 21 May 2026 |
| Event | 36th Medical Informatics Europe Conference, MIE 2026 - Genoa, Italy Duration: 25 May 2026 → 28 May 2026 |
Publication series
| Name | Studies in Health Technology and Informatics |
|---|---|
| Volume | 336 |
| ISSN (Print) | 0926-9630 |
| ISSN (Electronic) | 1879-8365 |
Conference
| Conference | 36th Medical Informatics Europe Conference, MIE 2026 |
|---|---|
| Country/Territory | Italy |
| City | Genoa |
| Period | 25/05/26 → 28/05/26 |
Bibliographical note
Publisher Copyright:© 2026 The Authors.
Keywords
- LLM hallucination
- LLM temperature
- LLMs
- determinants of health
- medical ontologies
- ontology expansion
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