Consistency checks to improve measurement with the Montgomery-Asberg Depression Rating Scale (MADRS)

ISCTM ALGORITHMS/FLAGS TO IDENTIFY CLINICAL INCONSISTENCY IN THE USE OF RATING SCALES IN CNS RCTs working group members

Research output: Contribution to journalArticlepeer-review

10 Scopus citations
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Abstract

International Society for CNS Clinical Trials and Methodology convened an expert Working Group that assembled consistency/inconsistency flags for the Montgomery-Asberg Depression Rating Scale (MADRS). Twenty-two flags were identified. Seven flags are believed to be strong flags that suggest that a thorough review of rating is warranted. The flags were applied to assessments derived from the NEWMEDS data repository. Almost 65% of ratings had at least one inconsistency flag raised and 22% had two or more. Application of flags to clinical ratings may improve reliability of ratings and validity of trials.

Original languageEnglish
Pages (from-to)143-147
Number of pages5
JournalJournal of Affective Disorders
Volume256
DOIs
StatePublished - 1 Sep 2019

Bibliographical note

Publisher Copyright:
© 2019

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