Conformational analysis of polymethylated derivatives of piperidine by the method of molecular mechanics

A. M. Belostotskii; T. V. Timofeeva; A. B. Shapiro; Yu T. Struchkov

doi:10.1007/bf00959634

Conformational analysis of polymethylated derivatives of piperidine by the method of molecular mechanics

A. M. Belostotskii, T. V. Timofeeva, A. B. Shapiro, Yu T. Struchkov

Research output: Contribution to journal › Article › peer-review

2 Scopus citations

Abstract

The conformational (steric) energies of different conformers and thus the type of dominant conformation were determined by the method of molecular mechanics for polysubstituted derivatives of piperidine. The chair conformation dominates for polymethylated 4-piperidines. The half-chair conformation is preferred for 1-methyl-3-methylene-4-piperidone, and the sofa conformation is preferred for analogous polymethylated enones.

Original language	English
Pages (from-to)	77-82
Number of pages	6
Journal	Bulletin of the Academy of Sciences of the USSR Division of Chemical Science
Volume	40
Issue number	1
DOIs	https://doi.org/10.1007/bf00959634
State	Published - Jan 1991
Externally published	Yes

Access to Document

10.1007/bf00959634

Cite this

@article{65492f7fdb944046a972a4d12e9ef9e4,

title = "Conformational analysis of polymethylated derivatives of piperidine by the method of molecular mechanics",

abstract = "The conformational (steric) energies of different conformers and thus the type of dominant conformation were determined by the method of molecular mechanics for polysubstituted derivatives of piperidine. The chair conformation dominates for polymethylated 4-piperidines. The half-chair conformation is preferred for 1-methyl-3-methylene-4-piperidone, and the sofa conformation is preferred for analogous polymethylated enones.",

author = "Belostotskii, {A. M.} and Timofeeva, {T. V.} and Shapiro, {A. B.} and Struchkov, {Yu T.}",

year = "1991",

month = jan,

doi = "10.1007/bf00959634",

language = "אנגלית",

volume = "40",

pages = "77--82",

journal = "Bulletin of the Academy of Sciences of the USSR Division of Chemical Science",

issn = "0568-5230",

publisher = "Springer New York",

number = "1",

}

TY - JOUR

T1 - Conformational analysis of polymethylated derivatives of piperidine by the method of molecular mechanics

AU - Belostotskii, A. M.

AU - Timofeeva, T. V.

AU - Shapiro, A. B.

AU - Struchkov, Yu T.

PY - 1991/1

Y1 - 1991/1

N2 - The conformational (steric) energies of different conformers and thus the type of dominant conformation were determined by the method of molecular mechanics for polysubstituted derivatives of piperidine. The chair conformation dominates for polymethylated 4-piperidines. The half-chair conformation is preferred for 1-methyl-3-methylene-4-piperidone, and the sofa conformation is preferred for analogous polymethylated enones.

AB - The conformational (steric) energies of different conformers and thus the type of dominant conformation were determined by the method of molecular mechanics for polysubstituted derivatives of piperidine. The chair conformation dominates for polymethylated 4-piperidines. The half-chair conformation is preferred for 1-methyl-3-methylene-4-piperidone, and the sofa conformation is preferred for analogous polymethylated enones.

UR - http://www.scopus.com/inward/record.url?scp=0003060958&partnerID=8YFLogxK

U2 - 10.1007/bf00959634

DO - 10.1007/bf00959634

M3 - ???researchoutput.researchoutputtypes.contributiontojournal.article???

AN - SCOPUS:0003060958

SN - 0568-5230

VL - 40

SP - 77

EP - 82

JO - Bulletin of the Academy of Sciences of the USSR Division of Chemical Science

JF - Bulletin of the Academy of Sciences of the USSR Division of Chemical Science

IS - 1

ER -

Conformational analysis of polymethylated derivatives of piperidine by the method of molecular mechanics

Abstract

Access to Document

Other files and links

Fingerprint

Cite this