Concurrent validity of negative symptom assessments in treatment refractory schizophrenia: Relationship between interview-based ratings and inpatient ward observations

Elizabeth A. Gilbert, Robert P. Liberman, Joseph Ventura, Robert Kern, Mary Jane Robertson, Sun Hwang, Michael F. Green

Research output: Contribution to journalArticlepeer-review

5 Scopus citations

Abstract

The concurrent validity of interview-based ratings of negative symptoms in 35 inpatients with chronic, treatment refractory schizophrenia was evaluated. Correlations were examined between interview-based ratings of negative symptoms, measured by the Brief Psychiatric Rating Scale and the Positive and Negative Syndrome Scale, and the naturalistic behavior of inpatients as assessed by the Time Sample Behavior Checklist. Higher levels of interview-based negative symptoms were related to reduced interpersonal activity on the inpatient ward, but not to entertainment, instrumental or self-maintenance activities. These findings offer partial support for the concurrent validity of office-based ratings of negative symptoms, and highlight the importance of longitudinal observations of patients for accurate identification of negative symptoms.

Original languageEnglish
Pages (from-to)443-447
Number of pages5
JournalJournal of Psychiatric Research
Volume34
Issue number6
DOIs
StatePublished - 2000
Externally publishedYes

Bibliographical note

Funding Information:
This study was supported in part by the UCLA Intervention Research Center for Schizophrenia and Psychiatric Rehabilitation (NIMH grant MH30911, R.P.L., P.I.) and an investigator-initiated grant from the Janssen Research Foundation (M.F.G., and B.D. Marshall, Co-P.I.s). The authors wish to thank Jeffery Hayden, Sharon Mitchell, M.S., Shirley Glynn, PhD. and the late B.D. Marshall Jr., M.D. for their help with this project. We would like to especially thank the nursing staff of the Camarillo-UCLA Clinical Research Unit of Camarillo State Hospital for their collection of observational data.

Funding

This study was supported in part by the UCLA Intervention Research Center for Schizophrenia and Psychiatric Rehabilitation (NIMH grant MH30911, R.P.L., P.I.) and an investigator-initiated grant from the Janssen Research Foundation (M.F.G., and B.D. Marshall, Co-P.I.s). The authors wish to thank Jeffery Hayden, Sharon Mitchell, M.S., Shirley Glynn, PhD. and the late B.D. Marshall Jr., M.D. for their help with this project. We would like to especially thank the nursing staff of the Camarillo-UCLA Clinical Research Unit of Camarillo State Hospital for their collection of observational data.

FundersFunder number
Janssen Research Foundation
National Institute of Mental HealthP30MH030911
University of California, Los Angeles

    Keywords

    • Behavioral assessment
    • Negative symptoms
    • Schizophrenia
    • Validity

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