TY - JOUR
T1 - Comparative Review of the Conserved UL24 Protein Family in Herpesviruses
AU - Orbaum-Harel, Odelia
AU - Sarid, Ronit
N1 - Publisher Copyright:
© 2024 by the authors.
PY - 2024/10/19
Y1 - 2024/10/19
N2 - The UL24 protein family, conserved across all subfamilies of Orthoherpesviridae, plays diverse and significant roles in viral replication, host–virus interactions and pathogenesis. Understanding the molecular mechanisms and interactions of UL24 proteins is key to unraveling the complex interplay between herpesviruses and their hosts. This review provides a comparative and comprehensive overview of current knowledge on UL24 family members, including their conservation, expression patterns, cellular localization, and functional roles upon their expression and during viral infection, highlighting their significance in herpesvirus biology and their potential functions.
AB - The UL24 protein family, conserved across all subfamilies of Orthoherpesviridae, plays diverse and significant roles in viral replication, host–virus interactions and pathogenesis. Understanding the molecular mechanisms and interactions of UL24 proteins is key to unraveling the complex interplay between herpesviruses and their hosts. This review provides a comparative and comprehensive overview of current knowledge on UL24 family members, including their conservation, expression patterns, cellular localization, and functional roles upon their expression and during viral infection, highlighting their significance in herpesvirus biology and their potential functions.
KW - ORF35
KW - UL24
KW - UL76
KW - herpesvirus
KW - open reading frame 20 (ORF20)
UR - http://www.scopus.com/inward/record.url?scp=85207376355&partnerID=8YFLogxK
U2 - 10.3390/ijms252011268
DO - 10.3390/ijms252011268
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C2 - 39457049
AN - SCOPUS:85207376355
SN - 1661-6596
VL - 25
JO - International Journal of Molecular Sciences
JF - International Journal of Molecular Sciences
IS - 20
M1 - 11268
ER -