Comparative review of interferometric detection of plasmonic nanoparticles

Adam Wax, Amihai Meiri, Siddarth Arumugam, Matthew T. Rinehart

Research output: Contribution to journalArticlepeer-review

3 Scopus citations


Noble metal nanoparticles exhibit enhanced scattering and absorption at specific wavelengths due to a localized surface plamson resonance. This unique property can be exploited to enable the use of plasmonic nanoparticles as contrast agents in optical imaging. A range of optical techniques have been developed to detect nanoparticles in order to implement imaging schemes. Here we review several different approaches for using optical interferometry to detect the presence and concentration of nanoparticles. The strengths and weaknesses of the various approaches are discussed and quantitative comparisons of the achievable signal to noise ratios are presented. The benefits of each approach are outlined as they relate to specific application goals.

Original languageEnglish
Pages (from-to)2166-2178
Number of pages13
JournalBiomedical Optics Express
Issue number10
StatePublished - 2013
Externally publishedYes


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