Cognitive control enhancement in attention deficit hyperactivity disorder (ADHD) and neurotypical individuals

Hodaya Weinberg, Yuval Baruch, Hila Tzameret, Michal Lavidor

Research output: Contribution to journalArticlepeer-review


Cognitive control, which has been localized to the right inferior frontal gyrus (rIFG) based on functional imaging and brain lesion studies, is impaired in patients with ADHD. The present study aims to investigate whether transcranial direct current stimulation (tDCS) over the rIFG might improve cognitive control in ADHD subjects. We hypothesized poorer performance in a cognitive control task, but not in a control language task, in the ADHD subjects. Crucially, following tDCS, we expected the ADHD group to improve their cognitive control. In a double-blind randomized control trial, 42 participants performed the stop signal task (SST) to index their cognitive control level and the language task. Half of them were randomly assigned to the anodal stimulation condition and half to the sham stimulation. The anodal or sham stimulation was applied over the right IFG. Following the stimulation, the participants reset the two tasks to see whether stimulation improved the (predicted) weaker performance in the ADHD group. Stimulation significantly enhanced cognitive control for both groups, with or without ADHD, in the SST task, but no significant stimulation effects were found for the control task. tDCS seems as a promising tool to improve cognitive control in the general population.

Original languageEnglish
Pages (from-to)2381-2392
Number of pages12
JournalExperimental Brain Research
Issue number9
StatePublished - Sep 2023

Bibliographical note

Publisher Copyright:
© 2023, The Author(s), under exclusive licence to Springer-Verlag GmbH Germany, part of Springer Nature.


  • ADHD
  • Cognitive control
  • rIFG
  • tDCS


Dive into the research topics of 'Cognitive control enhancement in attention deficit hyperactivity disorder (ADHD) and neurotypical individuals'. Together they form a unique fingerprint.

Cite this