Utilizing methods from nonlinear dynamics and a network approach we investigate the interactions between physiologic organ systems. We demonstrate that these systems can exhibit multiple forms of coupling that are independent from each other and act on different time scales. We also find that physiologic systems interaction is of transient nature with intermittent “on” and “off” periods, and that different forms of coupling can simultaneously coexist representing different aspects of physiologic regulation. We investigate the network of physiologic interactions between the brain, cardiac and respiratory systems across different sleep stages, well-defined physiologic states with distinct neuroautonomic regulation, and we uncover a strong relationship between network connectivity, patterns in network links strength and physiologic function. We show that physiologic networks exhibit pronounced phase transitions associated with reorganization in network structure and links strength in response to transitions across physiologic states.
|Title of host publication
|Nonlinear Dynamics of Electronic Systems - 22nd International Conference, NDES 2014, Proceedings
|Valeri M. Mladenov, Plamen Ch. Ivanov
|Number of pages
|Published - 2014
|22nd International Conference on Nonlinear Dynamics of Electronic Systems, NDES 2014 - Albena, Bulgaria
Duration: 4 Jul 2014 → 6 Jul 2014
|Communications in Computer and Information Science
|22nd International Conference on Nonlinear Dynamics of Electronic Systems, NDES 2014
|4/07/14 → 6/07/14
Bibliographical notePublisher Copyright:
© 2014 Springer International Publishing Switzerland.
- Cardio-respiratory coupling
- Phase synchronization