TY - JOUR
T1 - Coexistence of several unbalanced translocations in a case of neuroblastoma
T2 - The contribution of multicolor spectral karyotyping
AU - Trakhtenbrot, Luba
AU - Cohen, Ninette
AU - Rosner, Esther
AU - Gipsh, Nelly
AU - Brok-Simoni, Frida
AU - Mandel, Matilda
AU - Amariglio, Ninette
AU - Rechavi, Gideon
PY - 1999/7/15
Y1 - 1999/7/15
N2 - Spectral karyotyping (SKY) is based on the simultaneous hybridization of a set of 24 chromosome-specific DNA painting probes, each labeled with a different fluor combination. Automatic classification, based on the measurement of the spectrum for each chromosome, was applied to metaphases obtained from the affected bone marrow of a neuroblastoma case. Spectral karyotyping allowed the identification of chromosomal aberrations that could not be identified by the use of the G-banding technique, and revealed a number of gains and unbalanced translocations. Copyright (C) 1999 Elsevier Science Inc.
AB - Spectral karyotyping (SKY) is based on the simultaneous hybridization of a set of 24 chromosome-specific DNA painting probes, each labeled with a different fluor combination. Automatic classification, based on the measurement of the spectrum for each chromosome, was applied to metaphases obtained from the affected bone marrow of a neuroblastoma case. Spectral karyotyping allowed the identification of chromosomal aberrations that could not be identified by the use of the G-banding technique, and revealed a number of gains and unbalanced translocations. Copyright (C) 1999 Elsevier Science Inc.
UR - http://www.scopus.com/inward/record.url?scp=0033031587&partnerID=8YFLogxK
U2 - 10.1016/S0165-4608(98)00263-5
DO - 10.1016/S0165-4608(98)00263-5
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C2 - 10686937
AN - SCOPUS:0033031587
SN - 0165-4608
VL - 112
SP - 119
EP - 123
JO - Cancer Genetics and Cytogenetics
JF - Cancer Genetics and Cytogenetics
IS - 2
ER -