Abstract
Maternal behavior is regulated by several neurotransmitters, neuropeptides, and hormones. This mini-review focuses on the role of cholecystokinin (CCK), a neuropeptide and gut hormone best known as a satiety signal, in mediating maternal behavior. In addition to the role of CCK in the infant in mother-infant interactions, maternal CCK appears to also be important. We discuss maternal behavior research, mainly in rats, that has examined the effect of administering CCK to dams, CCK-opioid interactions, and maternal behavior in rats that lack CCK1 receptors. We discuss the possibility that CCK might play a role in neurological adjustments during pregnancy that ultimately influence behavioral adaptations by the offspring during lactation. Finally, we hypothesize that maternal CCK is also involved in maternal memory and reward.
| Original language | English |
|---|---|
| Pages (from-to) | 279-286 |
| Number of pages | 8 |
| Journal | Psychology and Neuroscience |
| Volume | 6 |
| Issue number | 3 |
| DOIs | |
| State | Published - Jul 2013 |
Keywords
- CCK
- Lactation
- Maternal behavior
- Nutrition
- Opioid
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