TY - JOUR
T1 - Cholecystokinin modulation of maternal behavior
AU - Felicio, Luciano Freitas
AU - Cruz, Aline de Mello
AU - Schroeder, Mariana
AU - Weller, Aron
PY - 2013/7
Y1 - 2013/7
N2 - Maternal behavior is regulated by several neurotransmitters, neuropeptides, and hormones. This mini-review focuses on the role of cholecystokinin (CCK), a neuropeptide and gut hormone best known as a satiety signal, in mediating maternal behavior. In addition to the role of CCK in the infant in mother-infant interactions, maternal CCK appears to also be important. We discuss maternal behavior research, mainly in rats, that has examined the effect of administering CCK to dams, CCK-opioid interactions, and maternal behavior in rats that lack CCK1 receptors. We discuss the possibility that CCK might play a role in neurological adjustments during pregnancy that ultimately influence behavioral adaptations by the offspring during lactation. Finally, we hypothesize that maternal CCK is also involved in maternal memory and reward.
AB - Maternal behavior is regulated by several neurotransmitters, neuropeptides, and hormones. This mini-review focuses on the role of cholecystokinin (CCK), a neuropeptide and gut hormone best known as a satiety signal, in mediating maternal behavior. In addition to the role of CCK in the infant in mother-infant interactions, maternal CCK appears to also be important. We discuss maternal behavior research, mainly in rats, that has examined the effect of administering CCK to dams, CCK-opioid interactions, and maternal behavior in rats that lack CCK1 receptors. We discuss the possibility that CCK might play a role in neurological adjustments during pregnancy that ultimately influence behavioral adaptations by the offspring during lactation. Finally, we hypothesize that maternal CCK is also involved in maternal memory and reward.
KW - CCK
KW - Lactation
KW - Maternal behavior
KW - Nutrition
KW - Opioid
UR - http://www.scopus.com/inward/record.url?scp=84890928787&partnerID=8YFLogxK
U2 - 10.3922/j.psns.2013.3.06
DO - 10.3922/j.psns.2013.3.06
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SN - 1984-3054
VL - 6
SP - 279
EP - 286
JO - Psychology and Neuroscience
JF - Psychology and Neuroscience
IS - 3
ER -