Chiral recognition via abundances of mixed chiral clusters

M. Nihamkin, A. Kaiser, I. Nemtsov, P. Martini, P. Scheier, Y. Mastai, Y. Toker

Research output: Contribution to journalArticlepeer-review

2 Scopus citations

Abstract

When chiral molecules form clusters in the gas phase their abundance often exhibits pronounced chiral effects. In this work we pose the question of whether and how this phenomena can be used for chiral recognition: whether by mixing a solution of a test molecule of unknown enantiomeric excess with a known homochiral probe molecule and measuring the abundance of the mixed clusters one can determine the enantiomeric excess of the test molecule. Focusing on mixed amino acid clusters, we will show that the technique is not general, but for many cases is applicable. In doing so, systematic trends governing cluster formation have to be understood, and are discussed below.

Original languageEnglish
Article number116215
JournalInternational Journal of Mass Spectrometry
Volume446
DOIs
StatePublished - Dec 2019

Bibliographical note

Publisher Copyright:
© 2019 Elsevier B.V.

Funding

This project was funded by the Israel Science Foundation , and Austrian Science Fund (FWF) , Project number P31149 and P289790 . A. Kaiser is grateful for the support of COST XLIC and Y. Toker is grateful for the support from the AIANI fellowship.

FundersFunder number
Austrian Science FundP31149, P289790
Israel Science Foundation

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