Chiral amplification in crystallization under ultrasound radiation

Dana D. Medina, Aharon Gedanken, Yitzhak Mastai

Research output: Contribution to journalArticlepeer-review

26 Scopus citations


Ultrasonic waves applied during the crystallization of slightly enantiomeric-enriched, supersaturated, aqueous solutions of dl-threonine lead to strong chiral amplifications (up to 90 % ee), particularly at the first stages of the crystallization process (see figure). The findings are confirmed by the optical rotation and circular-dichroism experiments of the crystallization solutions.

Original languageEnglish
Pages (from-to)11139-11142
Number of pages4
JournalChemistry - A European Journal
Issue number40
StatePublished - 26 Sep 2011


  • chiral amplification
  • chirality
  • kinetic resolution
  • sonochemistry
  • ultrasound


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