Chimeric avian-based screening system containing mammalian grafts

R. Goldstein (Inventor), Tamar Tennenbaum (Inventor), Varda Deutsch (Inventor)

Research output: Patent


The present invention relates to animal model systems comprising a chimera between an avian embryo and a mammalian organism. Specifically, chimeric model systems comprising normal, diseased or genetically transformed mammalian cells and tissues transplanted into avian embryos, and uses thereof for in vivo testing of drugs and therapeutic modalities are disclosed.
Original languageEnglish
Patent number8,324,447
StatePublished - 2012

Bibliographical note

PCT Publication Date: May 1, 2006. USPTO publication date, April 2009, patent granted 2012


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