Characteristics associated with COVID-19 vaccine uptake among adults aged 50 years and above in England (8 December 2020-17 May 2021): a population-level observational study

Elise Tessier; Yuma Rai; Eleanor Clarke; Anissa Lakhani; Camille Tsang; Ashley Makwana; Heather Heard; Tim Rickeard; Shreya Lakhani; Partho Roy; Michael Edelstein; Mary Ramsay; Jamie Lopez-Bernal; Joanne White; Nick Andrews; Colin N.J. Campbell; Julia Stowe

doi:10.1136/bmjopen-2021-055278

Characteristics associated with COVID-19 vaccine uptake among adults aged 50 years and above in England (8 December 2020-17 May 2021): a population-level observational study

Elise Tessier
, Yuma Rai
, Eleanor Clarke
, Anissa Lakhani
, Camille Tsang
, Ashley Makwana
, Heather Heard
, Tim Rickeard
, Shreya Lakhani
, Partho Roy
, Michael Edelstein
, Mary Ramsay
, Jamie Lopez-Bernal
, Joanne White
, Nick Andrews
, Colin N.J. Campbell
, Julia Stowe

Bar-Ilan University - Azrieli Faculty of Medicine

UK Health Security Agency

Research output: Contribution to journal › Article › peer-review

17 Scopus citations

Abstract

Objective To determine characteristics associated with COVID-19 vaccine coverage among individuals aged 50 years and above in England since the beginning of the programme. Design Observational cross-sectional study assessed by logistic regression and mean prevalence margins. Setting COVID-19 vaccinations delivered in England from 8 December 2020 to 17 May 2021. Participants 30 624 257/61 967 781 (49.4%) and 17 360 045/61 967 781 (28.1%) individuals in England were recorded as vaccinated in the National Immunisation Management System with a first dose and a second dose of a COVID-19 vaccine, respectively. Interventions Vaccination status with COVID-19 vaccinations. Main outcome measures Proportion, adjusted ORs and mean prevalence margins for individuals not vaccinated with dose 1 among those aged 50-69 years and dose 1 and 2 among those aged 70 years and above. Results Of individuals aged 50 years and above, black/African/Caribbean ethnic group was the least likely of all ethnic groups to be vaccinated with dose 1 of the COVID-19 vaccine. However, of those aged 70 years and above, the odds of not having dose 2 was 5.53 (95% CI 5.42 to 5.63) and 5.36 (95% CI 5.29 to 5.43) greater among Pakistani and black/African/Caribbean compared with white British ethnicity, respectively. The odds of not receiving dose 2 was 1.18 (95% CI 1.16 to 1.20) higher among individuals who lived in a care home compared with those who did not. This was the opposite to that observed for dose 1, where the odds of being unvaccinated was significantly higher among those not living in a care home (0.89 (95% CI 0.87 to 0.91)). Conclusions We found that there are characteristics associated with low COVID-19 vaccine coverage. Inequalities, such as ethnicity are a major contributor to suboptimal coverage and tailored interventions are required to improve coverage and protect the population from SARS-CoV-2.

Original language	English
Article number	e055278
Journal	BMJ Open
Volume	12
Issue number	3
DOIs	https://doi.org/10.1136/bmjopen-2021-055278
State	Published - 1 Mar 2022

Bibliographical note

Publisher Copyright:
© Author(s) (or their employer(s)) 2022. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ.

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

Keywords

COVID-19
health policy
public health

Access to Document

10.1136/bmjopen-2021-055278

Cite this

Tessier, E., Rai, Y., Clarke, E., Lakhani, A., Tsang, C., Makwana, A., Heard, H., Rickeard, T., Lakhani, S., Roy, P., Edelstein, M., Ramsay, M., Lopez-Bernal, J., White, J., Andrews, N., Campbell, C. N. J., & Stowe, J. (2022). Characteristics associated with COVID-19 vaccine uptake among adults aged 50 years and above in England (8 December 2020-17 May 2021): a population-level observational study. BMJ Open, 12(3), Article e055278. https://doi.org/10.1136/bmjopen-2021-055278

@article{d89753ab9d304187b2f7293bfab936cc,

title = "Characteristics associated with COVID-19 vaccine uptake among adults aged 50 years and above in England (8 December 2020-17 May 2021): a population-level observational study",

abstract = "Objective To determine characteristics associated with COVID-19 vaccine coverage among individuals aged 50 years and above in England since the beginning of the programme. Design Observational cross-sectional study assessed by logistic regression and mean prevalence margins. Setting COVID-19 vaccinations delivered in England from 8 December 2020 to 17 May 2021. Participants 30 624 257/61 967 781 (49.4\%) and 17 360 045/61 967 781 (28.1\%) individuals in England were recorded as vaccinated in the National Immunisation Management System with a first dose and a second dose of a COVID-19 vaccine, respectively. Interventions Vaccination status with COVID-19 vaccinations. Main outcome measures Proportion, adjusted ORs and mean prevalence margins for individuals not vaccinated with dose 1 among those aged 50-69 years and dose 1 and 2 among those aged 70 years and above. Results Of individuals aged 50 years and above, black/African/Caribbean ethnic group was the least likely of all ethnic groups to be vaccinated with dose 1 of the COVID-19 vaccine. However, of those aged 70 years and above, the odds of not having dose 2 was 5.53 (95\% CI 5.42 to 5.63) and 5.36 (95\% CI 5.29 to 5.43) greater among Pakistani and black/African/Caribbean compared with white British ethnicity, respectively. The odds of not receiving dose 2 was 1.18 (95\% CI 1.16 to 1.20) higher among individuals who lived in a care home compared with those who did not. This was the opposite to that observed for dose 1, where the odds of being unvaccinated was significantly higher among those not living in a care home (0.89 (95\% CI 0.87 to 0.91)). Conclusions We found that there are characteristics associated with low COVID-19 vaccine coverage. Inequalities, such as ethnicity are a major contributor to suboptimal coverage and tailored interventions are required to improve coverage and protect the population from SARS-CoV-2.",

keywords = "COVID-19, health policy, public health",

author = "Elise Tessier and Yuma Rai and Eleanor Clarke and Anissa Lakhani and Camille Tsang and Ashley Makwana and Heather Heard and Tim Rickeard and Shreya Lakhani and Partho Roy and Michael Edelstein and Mary Ramsay and Jamie Lopez-Bernal and Joanne White and Nick Andrews and Campbell, \{Colin N.J.\} and Julia Stowe",

note = "Publisher Copyright: {\textcopyright} Author(s) (or their employer(s)) 2022. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ.",

year = "2022",

month = mar,

day = "1",

doi = "10.1136/bmjopen-2021-055278",

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Tessier, E, Rai, Y, Clarke, E, Lakhani, A, Tsang, C, Makwana, A, Heard, H, Rickeard, T, Lakhani, S, Roy, P, Edelstein, M, Ramsay, M, Lopez-Bernal, J, White, J, Andrews, N, Campbell, CNJ & Stowe, J 2022, 'Characteristics associated with COVID-19 vaccine uptake among adults aged 50 years and above in England (8 December 2020-17 May 2021): a population-level observational study', BMJ Open, vol. 12, no. 3, e055278. https://doi.org/10.1136/bmjopen-2021-055278

TY - JOUR

T1 - Characteristics associated with COVID-19 vaccine uptake among adults aged 50 years and above in England (8 December 2020-17 May 2021)

T2 - a population-level observational study

AU - Tessier, Elise

AU - Rai, Yuma

AU - Clarke, Eleanor

AU - Lakhani, Anissa

AU - Tsang, Camille

AU - Makwana, Ashley

AU - Heard, Heather

AU - Rickeard, Tim

AU - Lakhani, Shreya

AU - Roy, Partho

AU - Edelstein, Michael

AU - Ramsay, Mary

AU - Lopez-Bernal, Jamie

AU - White, Joanne

AU - Andrews, Nick

AU - Campbell, Colin N.J.

AU - Stowe, Julia

PY - 2022/3/1

Y1 - 2022/3/1

N2 - Objective To determine characteristics associated with COVID-19 vaccine coverage among individuals aged 50 years and above in England since the beginning of the programme. Design Observational cross-sectional study assessed by logistic regression and mean prevalence margins. Setting COVID-19 vaccinations delivered in England from 8 December 2020 to 17 May 2021. Participants 30 624 257/61 967 781 (49.4%) and 17 360 045/61 967 781 (28.1%) individuals in England were recorded as vaccinated in the National Immunisation Management System with a first dose and a second dose of a COVID-19 vaccine, respectively. Interventions Vaccination status with COVID-19 vaccinations. Main outcome measures Proportion, adjusted ORs and mean prevalence margins for individuals not vaccinated with dose 1 among those aged 50-69 years and dose 1 and 2 among those aged 70 years and above. Results Of individuals aged 50 years and above, black/African/Caribbean ethnic group was the least likely of all ethnic groups to be vaccinated with dose 1 of the COVID-19 vaccine. However, of those aged 70 years and above, the odds of not having dose 2 was 5.53 (95% CI 5.42 to 5.63) and 5.36 (95% CI 5.29 to 5.43) greater among Pakistani and black/African/Caribbean compared with white British ethnicity, respectively. The odds of not receiving dose 2 was 1.18 (95% CI 1.16 to 1.20) higher among individuals who lived in a care home compared with those who did not. This was the opposite to that observed for dose 1, where the odds of being unvaccinated was significantly higher among those not living in a care home (0.89 (95% CI 0.87 to 0.91)). Conclusions We found that there are characteristics associated with low COVID-19 vaccine coverage. Inequalities, such as ethnicity are a major contributor to suboptimal coverage and tailored interventions are required to improve coverage and protect the population from SARS-CoV-2.

AB - Objective To determine characteristics associated with COVID-19 vaccine coverage among individuals aged 50 years and above in England since the beginning of the programme. Design Observational cross-sectional study assessed by logistic regression and mean prevalence margins. Setting COVID-19 vaccinations delivered in England from 8 December 2020 to 17 May 2021. Participants 30 624 257/61 967 781 (49.4%) and 17 360 045/61 967 781 (28.1%) individuals in England were recorded as vaccinated in the National Immunisation Management System with a first dose and a second dose of a COVID-19 vaccine, respectively. Interventions Vaccination status with COVID-19 vaccinations. Main outcome measures Proportion, adjusted ORs and mean prevalence margins for individuals not vaccinated with dose 1 among those aged 50-69 years and dose 1 and 2 among those aged 70 years and above. Results Of individuals aged 50 years and above, black/African/Caribbean ethnic group was the least likely of all ethnic groups to be vaccinated with dose 1 of the COVID-19 vaccine. However, of those aged 70 years and above, the odds of not having dose 2 was 5.53 (95% CI 5.42 to 5.63) and 5.36 (95% CI 5.29 to 5.43) greater among Pakistani and black/African/Caribbean compared with white British ethnicity, respectively. The odds of not receiving dose 2 was 1.18 (95% CI 1.16 to 1.20) higher among individuals who lived in a care home compared with those who did not. This was the opposite to that observed for dose 1, where the odds of being unvaccinated was significantly higher among those not living in a care home (0.89 (95% CI 0.87 to 0.91)). Conclusions We found that there are characteristics associated with low COVID-19 vaccine coverage. Inequalities, such as ethnicity are a major contributor to suboptimal coverage and tailored interventions are required to improve coverage and protect the population from SARS-CoV-2.

KW - COVID-19

KW - health policy

KW - public health

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JF - BMJ Open

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ER -

Characteristics associated with COVID-19 vaccine uptake among adults aged 50 years and above in England (8 December 2020-17 May 2021): a population-level observational study

Abstract

Bibliographical note

UN SDGs

Keywords

Access to Document

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