Changes of brain anatomy in patients with posttraumatic stress disorder: A pilot magnetic resonance imaging study

Michael S. Myslobodsky; Joseph Glicksohn; Jaffa Singer; Max Stern; Jacob Bar-Ziv; Nehemia Friedland; Avi Bleich

doi:10.1016/0165-1781(95)02708-5

Changes of brain anatomy in patients with posttraumatic stress disorder: A pilot magnetic resonance imaging study

Michael S. Myslobodsky
, Joseph Glicksohn
, Jaffa Singer
, Max Stern
, Jacob Bar-Ziv
, Nehemia Friedland
, Avi Bleich

Research output: Contribution to journal › Article › peer-review

49 Scopus citations

Abstract

No abnormalities in magnetic resonance images were recorded in patients with posttraumatic stress disorder other than an increased incidence (50%) of a small cleft in the callosal-septal interface, a cavum of the septum pellucidum. A similar grade of cavum was obtained in 14% of normal volunteers matched for age, socioeconomic background, and military experience. The cavum is believed to have antedated the disorder and is conceived to be a neurodevelopmental aberration. The possibility that the cavum is a marker of vulnerability to stress in psychopathology is discussed.

Original language	English
Pages (from-to)	259-264
Number of pages	6
Journal	Psychiatry Research
Volume	58
Issue number	3
DOIs	https://doi.org/10.1016/0165-1781(95)02708-5
State	Published - 16 Oct 1995
Externally published	Yes

Bibliographical note

Funding Information:
The researchr eportedh ere was partially sup-portedb y an internalg rantf rom Tel-Aviv University awardedt o M.S.M. J.G. was supportedb y a CharlesE . Smithp ostdoctorafle llowshipa nda re-searchg ranta wardedb y theN ational Institutef or Psychobiologyin Israel.A n earlierv ersiono f this report was presenteda t the Symposiumo n Biological Aspectso f Stressa nd PTSD in Bergen, Norway, in 1993.

Funding

The researchr eportedh ere was partially sup-portedb y an internalg rantf rom Tel-Aviv University awardedt o M.S.M. J.G. was supportedb y a CharlesE . Smithp ostdoctorafle llowshipa nda re-searchg ranta wardedb y theN ational Institutef or Psychobiologyin Israel.A n earlierv ersiono f this report was presenteda t the Symposiumo n Biological Aspectso f Stressa nd PTSD in Bergen, Norway, in 1993.

Funders
Tel Aviv University

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

Keywords

Cavum septi pellucidi
Magnetic resonance imaging
Neurodevelopment
Stress

Access to Document

10.1016/0165-1781(95)02708-5

Cite this

@article{f074203ebf8d4ce38e00c4ac910fb377,

title = "Changes of brain anatomy in patients with posttraumatic stress disorder: A pilot magnetic resonance imaging study",

abstract = "No abnormalities in magnetic resonance images were recorded in patients with posttraumatic stress disorder other than an increased incidence (50\%) of a small cleft in the callosal-septal interface, a cavum of the septum pellucidum. A similar grade of cavum was obtained in 14\% of normal volunteers matched for age, socioeconomic background, and military experience. The cavum is believed to have antedated the disorder and is conceived to be a neurodevelopmental aberration. The possibility that the cavum is a marker of vulnerability to stress in psychopathology is discussed.",

keywords = "Cavum septi pellucidi, Magnetic resonance imaging, Neurodevelopment, Stress",

author = "Myslobodsky, \{Michael S.\} and Joseph Glicksohn and Jaffa Singer and Max Stern and Jacob Bar-Ziv and Nehemia Friedland and Avi Bleich",

year = "1995",

month = oct,

day = "16",

doi = "10.1016/0165-1781(95)02708-5",

language = "אנגלית",

volume = "58",

pages = "259--264",

journal = "Psychiatry Research",

issn = "0165-1781",

publisher = "Elsevier Ireland Ltd",

number = "3",

}

TY - JOUR

T1 - Changes of brain anatomy in patients with posttraumatic stress disorder

T2 - A pilot magnetic resonance imaging study

AU - Myslobodsky, Michael S.

AU - Glicksohn, Joseph

AU - Singer, Jaffa

AU - Stern, Max

AU - Bar-Ziv, Jacob

AU - Friedland, Nehemia

AU - Bleich, Avi

PY - 1995/10/16

Y1 - 1995/10/16

N2 - No abnormalities in magnetic resonance images were recorded in patients with posttraumatic stress disorder other than an increased incidence (50%) of a small cleft in the callosal-septal interface, a cavum of the septum pellucidum. A similar grade of cavum was obtained in 14% of normal volunteers matched for age, socioeconomic background, and military experience. The cavum is believed to have antedated the disorder and is conceived to be a neurodevelopmental aberration. The possibility that the cavum is a marker of vulnerability to stress in psychopathology is discussed.

AB - No abnormalities in magnetic resonance images were recorded in patients with posttraumatic stress disorder other than an increased incidence (50%) of a small cleft in the callosal-septal interface, a cavum of the septum pellucidum. A similar grade of cavum was obtained in 14% of normal volunteers matched for age, socioeconomic background, and military experience. The cavum is believed to have antedated the disorder and is conceived to be a neurodevelopmental aberration. The possibility that the cavum is a marker of vulnerability to stress in psychopathology is discussed.

KW - Cavum septi pellucidi

KW - Magnetic resonance imaging

KW - Neurodevelopment

KW - Stress

UR - https://www.scopus.com/pages/publications/0028849985

U2 - 10.1016/0165-1781(95)02708-5

DO - 10.1016/0165-1781(95)02708-5

M3 - ???researchoutput.researchoutputtypes.contributiontojournal.article???

C2 - 8570781

SN - 0165-1781

VL - 58

SP - 259

EP - 264

JO - Psychiatry Research

JF - Psychiatry Research

IS - 3

ER -

Changes of brain anatomy in patients with posttraumatic stress disorder: A pilot magnetic resonance imaging study

Abstract

Bibliographical note

Funding

UN SDGs

Keywords

Access to Document

Other files and links

Fingerprint

Cite this