Changes of brain anatomy in patients with posttraumatic stress disorder: A pilot magnetic resonance imaging study

Michael S. Myslobodsky; Joseph Glicksohn; Jaffa Singer; Max Stern; Jacob Bar-Ziv; Nehemia Friedland; Avi Bleich

doi:10.1016/0165-1781(95)02708-5

Changes of brain anatomy in patients with posttraumatic stress disorder: A pilot magnetic resonance imaging study

Michael S. Myslobodsky, Joseph Glicksohn, Jaffa Singer, Max Stern, Jacob Bar-Ziv, Nehemia Friedland, Avi Bleich

Research output: Contribution to journal › Article › peer-review

49 Scopus citations

Abstract

No abnormalities in magnetic resonance images were recorded in patients with posttraumatic stress disorder other than an increased incidence (50%) of a small cleft in the callosal-septal interface, a cavum of the septum pellucidum. A similar grade of cavum was obtained in 14% of normal volunteers matched for age, socioeconomic background, and military experience. The cavum is believed to have antedated the disorder and is conceived to be a neurodevelopmental aberration. The possibility that the cavum is a marker of vulnerability to stress in psychopathology is discussed.

Original language	English
Pages (from-to)	259-264
Number of pages	6
Journal	Psychiatry Research
Volume	58
Issue number	3
DOIs	https://doi.org/10.1016/0165-1781(95)02708-5
State	Published - 16 Oct 1995
Externally published	Yes

Bibliographical note

Funding Information:
The researchr eportedh ere was partially sup-portedb y an internalg rantf rom Tel-Aviv University awardedt o M.S.M. J.G. was supportedb y a CharlesE . Smithp ostdoctorafle llowshipa nda re-searchg ranta wardedb y theN ational Institutef or Psychobiologyin Israel.A n earlierv ersiono f this report was presenteda t the Symposiumo n Biological Aspectso f Stressa nd PTSD in Bergen, Norway, in 1993.

Keywords

Cavum septi pellucidi
Magnetic resonance imaging
Neurodevelopment
Stress

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10.1016/0165-1781(95)02708-5

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Changes of brain anatomy in patients with posttraumatic stress disorder: A pilot magnetic resonance imaging study

Abstract

Bibliographical note

Keywords

UN SDGs

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