TY - JOUR
T1 - Cement-Induced Chromate Occupational Allergic Contact Dermatitis
AU - Kridin, Khalaf
AU - Bergman, Reuven
AU - Khamaisi, Mogher
AU - Zelber-Sagi, Shira
AU - Weltfriend, Sara
N1 - Publisher Copyright:
© 2016 American Contact Dermatitis Society. All Rights Reserved.
PY - 2016/7/1
Y1 - 2016/7/1
N2 - Background Hexavalent chromium in cement is a common cause of occupational allergic contact dermatitis (OACD). Methods Analysis of patch test data during 1999 to 2013 was done. Patients with cement-induced chromate OACD filled the Dermatology Life Quality Index, graded 1 to 5. Results Of 4846 consecutive patients who were patch tested, 146 (3%) were chromate-sensitive. Of 46 (31.5%) who presented with chromate OACD, 27 (59%) had cement-induced chromate OACD. The proportion of chromate-sensitive patients with clinically relevant cement exposure increased from 7.7% in 2002 to 2004 to 28.7% in 2011 to 2013 (P = 0.04). The median age of presentation was younger than for other chromate-sensitive patients (32 vs 42 years). Hand eczema (88.9%) was the most frequent clinical presentation. Of the 27 with cement-induced chromate OACD, 21 (77.8%) had ongoing dermatitis at the time of the review. Although 14/27 (51.9%) changed their occupation to avoid exposure to cement, symptoms persisted in 9/14 (64.3%). Prolonged exposure to cement before development of symptoms was associated with chronicity. All the symptomatic patients experienced at least a moderate effect on their quality of life (grade 3 or higher on the Dermatology Life Quality Index). Conclusions We recommend the adoption of the European legislation in Israel, to reduce the prevalence of chromate OACD from cement.
AB - Background Hexavalent chromium in cement is a common cause of occupational allergic contact dermatitis (OACD). Methods Analysis of patch test data during 1999 to 2013 was done. Patients with cement-induced chromate OACD filled the Dermatology Life Quality Index, graded 1 to 5. Results Of 4846 consecutive patients who were patch tested, 146 (3%) were chromate-sensitive. Of 46 (31.5%) who presented with chromate OACD, 27 (59%) had cement-induced chromate OACD. The proportion of chromate-sensitive patients with clinically relevant cement exposure increased from 7.7% in 2002 to 2004 to 28.7% in 2011 to 2013 (P = 0.04). The median age of presentation was younger than for other chromate-sensitive patients (32 vs 42 years). Hand eczema (88.9%) was the most frequent clinical presentation. Of the 27 with cement-induced chromate OACD, 21 (77.8%) had ongoing dermatitis at the time of the review. Although 14/27 (51.9%) changed their occupation to avoid exposure to cement, symptoms persisted in 9/14 (64.3%). Prolonged exposure to cement before development of symptoms was associated with chronicity. All the symptomatic patients experienced at least a moderate effect on their quality of life (grade 3 or higher on the Dermatology Life Quality Index). Conclusions We recommend the adoption of the European legislation in Israel, to reduce the prevalence of chromate OACD from cement.
UR - http://www.scopus.com/inward/record.url?scp=84979529917&partnerID=8YFLogxK
U2 - 10.1097/der.0000000000000203
DO - 10.1097/der.0000000000000203
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C2 - 27331340
AN - SCOPUS:84979529917
SN - 1710-3568
VL - 27
SP - 208
EP - 214
JO - Dermatitis
JF - Dermatitis
IS - 4
ER -