Cellunomics: The interaction analysis of cells

Virendra S. Gomase, Aravind K. Tripathi, Somnath Tagore

Research output: Contribution to journalArticlepeer-review

1 Scopus citations

Abstract

Cellunomics envisions the new branch of cell, which integrates genomics and proteomics with a new knowledge base built from temporal and spatial data on the chemical and molecular interrelationships of cellular components, i.e., cellome. Cellunomics helps in finding cell-specific protein and protein-protein interaction using cell-specific mRNA and protein repository. A flexible statistical-model-based clustering approach is introduced for identifying cell populations and the data revealed by the cellome is informational as well as physical. Cellunomics aids the automated, high-content platforms, to increase the scope and scale of experiments traditionally executed through interactive microscopy.

Original languageEnglish
Pages (from-to)674-690
Number of pages17
JournalInternational Journal of Bioinformatics Research and Applications
Volume5
Issue number6
DOIs
StatePublished - Oct 2009
Externally publishedYes

Keywords

  • Cellome
  • Chromatography
  • Cluster
  • Electrophoresis
  • Signalling
  • Spectrometry

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